P117 Inhibitors
P117 inhibitors are a class of chemical compounds that specifically target and block the activity of P117, a protein involved in cellular signaling and regulatory processes. While details about the exact nature and function of P117 may vary depending on the biological context, proteins with designations such as P117 often play roles in pathways that influence intracellular communication, protein-protein interactions, and signal transduction. By inhibiting P117, these compounds interfere with its ability to participate in these cellular processes, leading to disruptions in the pathways it regulates. P117 may act as a molecular switch or adapter, interacting with other proteins to facilitate the transmission of signals or regulate cellular responses to external stimuli. Inhibitors of P117 effectively prevent the protein from binding to its interaction partners, altering the normal flow of cellular communication.
The study of P117 inhibitors provides researchers with valuable tools to investigate the role of this protein in broader cellular networks. By blocking P117, scientists can observe changes in signaling pathways, gene expression, and protein interactions, which helps clarify the specific functions of the protein in various biological contexts. P117 inhibitors can also shed light on how this protein influences key cellular processes such as cell growth, differentiation, or response to environmental stress. The disruption of P117's activity can reveal insights into the molecular mechanisms that rely on this protein, allowing researchers to understand how it contributes to the regulation of cellular homeostasis and coordination within complex signaling networks. Through the use of these inhibitors, the broader implications of P117's involvement in intracellular dynamics can be explored in greater detail.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Chloramphenicol | 56-75-7 | sc-3594 | 25 g | $53.00 | 10 | |
Chloramphenicol targets bacterial and mitochondrial ribosomes, specifically inhibiting peptidyl transferase activity, which results in a reduction of mitochondrial protein synthesis, potentially leading to lower levels of P117. | ||||||
Mdivi-1 | 338967-87-6 | sc-215291 sc-215291B sc-215291A sc-215291C | 5 mg 10 mg 25 mg 50 mg | $66.00 $124.00 $246.00 $456.00 | 13 | |
Mdivi-1, a selective inhibitor of the mitochondrial division protein Drp1, disrupts mitochondrial fission processes, which could result in altered mitochondrial morphology and a subsequent decrease in the synthesis of structural components such as P117. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $146.00 $12250.00 | 18 | |
Oligomycin binds to the F0 subunit of ATP synthase, blocking proton flow and ATP synthesis. This disruption of ATP production can lead to a decrease in energy-dependent processes including the synthesis of mitochondrial proteins like P117. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $54.00 $62.00 $1642.00 $4600.00 | 51 | |
Antimycin A blocks electron transport by binding to cytochrome b in complex III, causing a severe reduction in electron transport chain activity and ATP production, which could result in decreased synthesis of mitochondrial proteins including P117. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $254.00 | 41 | |
Rotenone interferes with electron transport by inhibiting complex I, leading to a reduction in ATP production and possibly decreasing the synthesis of proteins critical for mitochondrial structure, such as P117. | ||||||
Carbonyl Cyanide m-Chlorophenylhydrazone | 555-60-2 | sc-202984A sc-202984 sc-202984B | 100 mg 250 mg 500 mg | $75.00 $150.00 $235.00 | 8 | |
Carbonyl Cyanide m-Chlorophenylhydrazone acts as a protonophore, dissipating the proton gradient across the mitochondrial membrane and uncoupling oxidative phosphorylation, which could lead to a decrease in mitochondrial energy efficiency and reduce the synthesis of proteins like P117. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates sirtuin pathways and AMPK, which enhances mitochondrial turnover and biogenesis. This increase in mitochondrial turnover might lead to changes in the expression levels of mitochondrial structural proteins, potentially reducing levels of P117. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin stimulates AMPK activity, which enhances cellular uptake of glucose and alters mitochondrial activity. This alteration can lead to a reduction in the synthesis of mitochondrial proteins such as P117. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
2-Deoxy-D-glucose is a glycolysis inhibitor that mimics glucose but cannot be fully metabolized, leading to decreased cellular energy production and a subsequent reduction in mitochondrial protein synthesis, including P117. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits the mTOR pathway, which is crucial for cell growth and protein synthesis. This inhibition can decrease the cellular capacity to synthesize mitochondrial proteins, potentially leading to reduced levels of P117. | ||||||