Date published: 2026-3-3

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OR4F3 Activators

OR4F3 activators belong to a specialized class of chemical compounds that have piqued the interest of researchers in the field of molecular biology and sensory perception. These compounds are intricately designed to modulate the activity of OR4F3, a protein-coding gene that is a part of the larger family of olfactory receptor (OR) genes. OR4F3, also known as Olfactory Receptor Family 4 Subfamily F Member 3, is primarily expressed in olfactory sensory neurons within the nasal epithelium and plays a pivotal role in the detection and recognition of specific odorant molecules. OR4F3 activators operate by targeting specific regulatory elements within the OR4F3 gene, typically located in promoter or enhancer regions, with the primary objective of enhancing its transcription and subsequent translation into functional olfactory receptors.

The mechanisms through which OR4F3 activators exert their effects may vary, but their central purpose is to act as molecular switches, amplifying the activity of OR4F3. Researchers are continually exploring the potential applications and implications of OR4F3 activation, aiming to deepen our understanding of how this gene contributes to the sense of smell and olfactory perception. This class of compounds holds promise for advancing our knowledge of sensory perception, particularly within the context of olfactory receptors, offering insights into the intricate mechanisms that govern our ability to detect and discriminate various odorant molecules and the significance of OR4F3 in the complex world of olfaction. OR4F3 activators serve as valuable tools in the ongoing exploration of molecular biology, providing opportunities to uncover the complex roles that OR4F3 plays in sensory functions and its potential involvement in shaping our olfactory experiences.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin activates adenylate cyclase, increasing cAMP levels, which may lead to the upregulation of OR4F3 expression through cAMP response element-binding protein (CREB) activation.

IBMX

28822-58-4sc-201188
sc-201188B
sc-201188A
200 mg
500 mg
1 g
$260.00
$350.00
$500.00
34
(1)

IBMX increases intracellular cAMP by inhibiting phosphodiesterases, potentially enhancing OR4F3 gene expression via cAMP-dependent pathways.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium butyrate is a histone deacetylase inhibitor that may alter chromatin structure and upregulate OR4F3 gene expression.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

Trichostatin A, another histone deacetylase inhibitor, could potentially increase the expression of genes like OR4F3 by modifying chromatin accessibility.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-Azacytidine is a DNA methyltransferase inhibitor that can lead to the demethylation and possible activation of genes, including potentially OR4F3.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid, an active metabolite of vitamin A, can regulate gene expression and may influence the expression of certain OR genes.

Theophylline

58-55-9sc-202835
sc-202835A
sc-202835B
5 g
25 g
100 g
$20.00
$32.00
$85.00
6
(0)

Theophylline increases cAMP levels by inhibiting phosphodiesterases, which might affect OR gene expression.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

Zinc ions play a role in modulating GPCR function and may affect the expression of OR genes.

Dimethyl Sulfoxide (DMSO)

67-68-5sc-202581
sc-202581A
sc-202581B
100 ml
500 ml
4 L
$31.00
$117.00
$918.00
136
(6)

DMSO is often used as a solvent in biological studies and can influence gene expression profiles in cells.

A23187

52665-69-7sc-3591
sc-3591B
sc-3591A
sc-3591C
1 mg
5 mg
10 mg
25 mg
$55.00
$131.00
$203.00
$317.00
23
(1)

A-23187 is a calcium ionophore that can alter intracellular signaling pathways, potentially affecting OR4F3 expression.