Date published: 2025-10-17

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Odf1 Inhibitors

Odf1 inhibitors represent a specialized class of chemical compounds that have garnered attention in the field of molecular biology and cellular structure research. Odf1, or Outer Dense Fiber 1, is a protein primarily found in the sperm tail where it plays a critical role in the formation and structural stability of the outer dense fibers. These fibers are essential for the maintenance of sperm tail integrity, motility, and overall sperm function. The term Odf1 inhibitors refers to a group of molecules meticulously designed to selectively target and modulate the activity of Odf1. These inhibitors serve as invaluable tools in laboratory investigations, enabling researchers to explore the intricate molecular functions and cellular processes associated with Odf1.

Odf1 inhibitors typically function by interfering with the interactions or functions of Odf1 within the sperm tail, potentially disrupting the assembly of outer dense fibers. This interference can lead to alterations in sperm tail structure and function, affecting various aspects of sperm motility and, consequently, fertilization potential. Researchers employ Odf1 inhibitors to gain insights into the physiological roles and molecular interactions of Odf1 within sperm cells, aiming to advance our understanding of the fundamental mechanisms involved in sperm structure and motility. Through the study of Odf1 inhibitors, scientists seek to unravel the complexities of sperm biology, cellular organization, and the broader field of reproductive biology, contributing to our knowledge of how sperm cells are uniquely adapted for their role in fertilization.

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Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Trichostatin A is a histone deacetylase inhibitor that can change chromatin structure and gene expression, potentially reducing Odf1 expression.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

5-Aza-2'-deoxycytidine, a DNA methyltransferase inhibitor, may alter methylation patterns and downregulate genes including Odf1.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Actinomycin D intercalates into DNA, inhibiting transcription broadly, which can decrease the expression of many genes, like Odf1.

Mithramycin A

18378-89-7sc-200909
1 mg
$54.00
6
(1)

Mithramycin A binds to GC-rich DNA sequences, potentially inhibiting transcription factors and reducing Odf1 expression.

Cisplatin

15663-27-1sc-200896
sc-200896A
100 mg
500 mg
$76.00
$216.00
101
(4)

Cisplatin forms DNA adducts and may broadly affect DNA replication and transcription, potentially reducing Odf1 expression.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

Triptolide has been shown to inhibit the transcription of various genes and might reduce Odf1 expression as part of its effect.

Mitomycin C

50-07-7sc-3514A
sc-3514
sc-3514B
2 mg
5 mg
10 mg
$65.00
$99.00
$140.00
85
(5)

Mitomycin C creates DNA cross-links that can inhibit DNA synthesis and transcription, possibly lowering Odf1 expression.

Vitamin K3

58-27-5sc-205990B
sc-205990
sc-205990A
sc-205990C
sc-205990D
5 g
10 g
25 g
100 g
500 g
$25.00
$35.00
$46.00
$133.00
$446.00
3
(1)

Menadione generates reactive oxygen species that can damage cellular components and might incidentally reduce Odf1 expression.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic Acid affects gene expression and differentiation, and could theoretically alter expression patterns of proteins like Odf1.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

Camptothecin inhibits DNA topoisomerase I, leading to reduced transcription and potentially diminished Odf1 expression.