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Odf1 Antibody (E-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects Odf1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Odf1 (E-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Odf1 protein plays a crucial role in the structural integrity of the outer dense fibers (ODF) in the mammalian sperm tail, which are essential for maintaining sperm elasticity and motility. These fibers are located outside the axoneme and are vital for the passive elastic properties and recoil of the sperm tail, which are necessary for effective swimming. ODFs are composed of a complex array of proteins, with Odf1 being one of the major components, alongside Odf2 and Odf3, all of which are predominantly expressed during spermiogenesis. Human Odf1 gene is located on chromosome 8q22, while Odf2 is found on chromosome 9q34, and both genes are exclusively expressed in the testis. Notably, Odf2 interacts with Odf1 through leucine zipper motifs, facilitating the assembly of the outer dense fibers, and Odf1 is also capable of self-interaction. Given their critical roles in sperm structure and function, abnormalities in Odf proteins may contribute to male infertility due to flagellar dysfunction, highlighting the importance of studying these proteins in reproductive biology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Odf1 Antibody (E-11) | sc-390152 | 200 µg/ml | $316.00 | |||
Odf1 Antibody (E-11): m-IgG1 BP-HRP Bundle | sc-531734 | 200 µg Ab; 20 µg BP | $354.00 | |||
Odf1 Antibody (E-11) AC | sc-390152 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Odf1 Antibody (E-11) HRP | sc-390152 HRP | 200 µg/ml | $316.00 | |||
Odf1 Antibody (E-11) FITC | sc-390152 FITC | 200 µg/ml | $330.00 | |||
Odf1 Antibody (E-11) PE | sc-390152 PE | 200 µg/ml | $343.00 | |||
Odf1 Antibody (E-11) Alexa Fluor® 488 | sc-390152 AF488 | 200 µg/ml | $357.00 | |||
Odf1 Antibody (E-11) Alexa Fluor® 546 | sc-390152 AF546 | 200 µg/ml | $357.00 | |||
Odf1 Antibody (E-11) Alexa Fluor® 594 | sc-390152 AF594 | 200 µg/ml | $357.00 | |||
Odf1 Antibody (E-11) Alexa Fluor® 647 | sc-390152 AF647 | 200 µg/ml | $357.00 | |||
Odf1 Antibody (E-11) Alexa Fluor® 680 | sc-390152 AF680 | 200 µg/ml | $357.00 | |||
Odf1 Antibody (E-11) Alexa Fluor® 790 | sc-390152 AF790 | 200 µg/ml | $357.00 | |||
Odf1 (E-11) Neutralizing Peptide | sc-390152 P | 100 µg/0.5 ml | $68.00 |