Oct-1 Inhibitors
Oct-1 inhibitors belong to a class of chemical compounds designed to target and modulate the activity of the Oct-1 transcription factor. Oct-1, short for Octamer-binding transcription factor 1, is a critical protein in the regulation of gene expression. It is a member of the POU domain family of transcription factors and plays a pivotal role in controlling the transcription of various genes involved in diverse biological processes. Oct-1 contains a POU-specific domain that allows it to bind to specific DNA sequences in the promoter regions of target genes. These DNA-binding interactions are vital for initiating and regulating the transcription of genes involved in cellular growth, differentiation, and development. Oct-1 inhibitors are engineered to interfere with Oct-1's binding to its target DNA sequences, thereby modulating gene expression and influencing various cellular functions.
The development of Oct-1 inhibitors is primarily driven by their applications in basic research and drug discovery. By selectively inhibiting Oct-1's activity, researchers can gain valuable insights into the specific genes and pathways that this transcription factor regulates. This knowledge is crucial for understanding various biological processes, including cell proliferation, immune response, and embryonic development.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, a natural compound found in turmeric, has been shown to modulate various signaling pathways and transcription factors, potentially leading to reduced Oct-1 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a polyphenol found in grapes and berries, has antioxidant properties and can modulate the activity of several transcription factors, possibly inhibiting Oct-1 expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, an isoflavone found in soy, has been shown to influence epigenetic modifications and transcription factor activity, potentially leading to downregulation of Oct-1. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid found in many fruits and vegetables, can modulate various signaling pathways and transcription factors, potentially inhibiting the expression of Oct-1. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane, found in cruciferous vegetables, can induce epigenetic changes and modulate transcription factor activity, potentially inhibiting Oct-1 expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat, a histone deacetylase inhibitor, can induce changes in chromatin structure, potentially leading to reduced expression of Oct-1 by altering its transcriptional activity. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate, a short-chain fatty acid, acts as a histone deacetylase inhibitor and has been shown to modulate gene expression, potentially inhibiting Oct-1. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A, a histone deacetylase inhibitor, can induce chromatin remodeling and alter gene expression, potentially leading to downregulation of Oct-1. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Decitabine is a DNA methyltransferase inhibitor that can cause DNA hypomethylation, potentially leading to the inhibition of Oct-1 expression by altering its transcriptional activity. | ||||||