OAT1 Activators
The chemical class of OAT1 Activators comprises various compounds that could potentially influence the activity of OAT1 indirectly through their effects on cellular transport mechanisms, electrolyte balance, and overall cellular environment. These activators do not interact directly with OAT1 but modulate the physiological conditions under which OAT1 functions, thereby influencing its transport activity. Compounds such as cAMP, Calcium Chloride, Magnesium Sulfate, and Potassium Chloride play pivotal roles in maintaining electrolyte balance and modulating cellular signaling pathways. Alterations in electrolyte concentrations and signaling cascades can indirectly influence the function of transporters like OAT1, which are critical in maintaining cellular homeostasis. Similarly, Forskolin and Sodium Butyrate, by increasing intracellular cAMP levels and affecting gene expression, respectively, can modulate cellular processes that indirectly affect OAT1's transport activity.
Additionally, endocrine factors like Insulin, Glucagon, Estradiol, and Dexamethasone, which regulate various aspects of cellular metabolism and physiological responses, can have an indirect impact on the functionality of OAT1. Metformin, an antidiabetic agent, affects cellular metabolic pathways, potentially influencing the activity of transporters involved in renal excretion, including OAT1.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $114.00 $175.00 $260.00 $362.00 $617.00 $1127.00 | ||
As a secondary messenger, cAMP can modulate various cellular processes that might influence OAT1 activity. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $65.00 $262.00 | 1 | |
Calcium ion alterations can affect cellular signaling pathways potentially influencing OAT1 activity. | ||||||
Magnesium sulfate anhydrous | 7487-88-9 | sc-211764 sc-211764A sc-211764B sc-211764C sc-211764D | 500 g 1 kg 2.5 kg 5 kg 10 kg | $45.00 $68.00 $160.00 $240.00 $410.00 | 3 | |
Modulates electrolyte balance, potentially affecting transport mechanisms involving OAT1. | ||||||
Potassium Chloride | 7447-40-7 | sc-203207 sc-203207A sc-203207B sc-203207C | 500 g 2 kg 5 kg 10 kg | $25.00 $56.00 $104.00 $183.00 | 5 | |
Potassium balance can influence cellular transport mechanisms, potentially affecting OAT1 function. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
An HDAC inhibitor, potentially influencing gene expression and protein function, including OAT1. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases intracellular cAMP levels, potentially modulating transport processes involving OAT1. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $42.00 $83.00 $155.00 | 7 | |
Nitric oxide can modulate cellular signaling and transport mechanisms, potentially influencing OAT1. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Influences cellular metabolism and transport processes, potentially affecting OAT1 activity. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
An antidiabetic drug that affects cellular metabolism, potentially influencing OAT1 activity. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
A hormone that modulates various cellular processes, potentially influencing OAT1 function. | ||||||