Sodium nitroprusside dihydrate CAS: 13755-38-9
MF: C5FeN6O•2Na•2H2O
MW: 297.95
A nitric oxide releasing compound.

Sodium nitroprusside dihydrate (CAS 13755-38-9)

Sodium nitroprusside dihydrate | CAS 13755-38-9 is rated 5.0 out of 5 by 1.
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Synonym: Sodium nitroferricyanide(III) dihydrate
Application: A nitric oxide releasing compound
CAS Number: 13755-38-9
Purity: ≥98%
Molecular Weight: 297.95
Molecular Formula: C5FeN6O•2Na•2H2O
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Sodium nitroprusside (SNP), Dihydrate, is a nitric oxide donor/releaser and potent vasodilator, which has been reported to reduce lipid peroxidation-induced membrane damage, and is believed to exert its vasodilating activity through the vascular activation of nitric oxide. SNP is useful for quantitative ammonium analysis, as well as chromatographic detection of cystine-containing peptides. It has also been reported to be beneficial in maintaining post-thaw sperm viability and motion for up to 6 hours, which has been attributed to the reduction of lipid peroxidative damage to the sperm membrane substances.


References

1. Kowaluk, E A., et al., 1992. Metabolic activation of sodium nitroprusside to nitric oxide in vascular smooth muscle. The Journal of pharmacology and experimental therapeutics. 262(3): 916-22. PMID: 1527732
2. Ignarro, L J., et al., 1981. Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates. The Journal of pharmacology and experimental therapeutics. 218(3): 739-49. PMID: 6115052
3. Hellstrom, W J., et al., 1994. Effect of sodium nitroprusside on sperm motility, viability, and lipid peroxidation. Fertility and sterility. 61(6): 1117-22. PMID: 8194627

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in water (400 g/l) at 20° C, and ethanol (slightly soluble).
Storage :
Store at room temperature
Density :
1.72 g/cm3 at 20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
LJ8925000
PubChem CID :
11953895
Merck Index :
14: 8649
MDL Number :
MFCD00149192
EC Number :
238-373-9
Beilstein Registry :
11818
SMILES :
[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[N-]=O.[Na+].[Na+].[Fe+4]

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Sodium nitroprusside dihydrate  Product Citations

See how others have used Sodium nitroprusside dihydrate. Click on the entry to view the PubMed entry .

Citations 1 to 6 of 6 total

PMID: # 27158388  Xu, Z. et al. 2016. Am J Transl Res. 8: 1027-36.

PMID: # 19479373  Svensson, G. et al. 2009. Glycoconj. J. 26: 1247-1257.

PMID: # 19202197  Kawachi, M. et al. 2008. Gen. Physiol. Biophys. 27: 243-252.

PMID: # 18502941  Dallabrida, SM. et al. 2008. FASEB J. 22: 3010-3023.

PMID: # 17997517  Wu, J. et al. 2007. J. Proteome Res. 6: 4728-4736.

PMID: # 16199577  Hahn, MY. et al. 2005. J. Bacteriol. 187: 7062-7071.

Citations 1 to 6 of 6 total
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Rated 5 out of 5 by from Tatsumi Tatsumi, R. et al. (PubMed 12181355) used Sodium nitroprusside dihydrate, a nitric oxide (NO) donor/releaser, to investigate the potential involvement of NO in hepatocyte growth factor (HGF) release and skeletal muscle satellite cell activation in response to mechanical stretch. In the absence of Sodium nitroprusside dihydrate, HGF was not released and satellite cell activation did not occur. -SCBT Publication Review
Date published: 2015-01-03
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