Date published: 2026-7-24

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NPC Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of NPC Antibodies for studying nucleoporins, essential components of the nuclear pore complex. NPC Antibodies are compatible with multiple research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Nucleoporins regulate the transport of molecules between the nucleus and cytoplasm, influencing gene expression and cellular signaling pathways. Their proper function maintains cellular homeostasis and enables responses to environmental changes. Dysregulation of nucleoporins has been linked to various diseases, including cancer and neurodegenerative disorders. Understanding nucleoporin function and regulation provides insights into fundamental cellular processes and potential therapeutic targets. Research using NPC monoclonal antibodies advances scientific knowledge of nuclear transport mechanisms and their roles in health and disease. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of nucleoporin biology and its implications for human health.

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NPC Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

NPC1 Antibody (G-1)

sc-271335mouse IgA516-630 (h)WB, IP, IF, ELISAm, r, h
2
(3)

NPC1 Antibody (E-9)

sc-271334mouse IgG2a κ516-630 (h)WB, IP, IF, ELISAh

new

(1)

NPC1L1 Antibody (G-1)

sc-166802mouse IgG2b κ20-32 (h)WB, IP, IF, ELISAm, r, h
18
(3)

NPC2 Antibody (D-3)

sc-166449mouse IgG2a κ21-145 (h)WB, IP, IF, ELISAm, r, h
4
(3)

NPC2 Antibody (H-10)

sc-166321mouse IgG2b κ21-145 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(2)

NPC siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NPC1 siRNA (h)

sc-41588hGene SilencingN/A
2
(0)

NPC1 shRNA Plasmid (h)

sc-41588-SHhGene SilencingPuromycin
2
(0)

NPC1 shRNA (h) Lentiviral Particles

sc-41588-VhGene SilencingPuromycin
2
(0)

NPC1 siRNA (m)

sc-41589mGene SilencingN/A
2
(0)

NPC1 shRNA Plasmid (m)

sc-41589-SHmGene SilencingPuromycin
2
(0)

NPC1 shRNA (m) Lentiviral Particles

sc-41589-VmGene SilencingPuromycin
2
(0)

NPC2 siRNA (h)

sc-43977hGene SilencingN/A
1
(0)

NPC2 shRNA Plasmid (h)

sc-43977-SHhGene SilencingPuromycin
1
(0)

NPC2 shRNA (h) Lentiviral Particles

sc-43977-VhGene SilencingPuromycin
1
(0)

NPC2 siRNA (m)

sc-44816mGene SilencingN/A0
(0)

NPC2 shRNA Plasmid (m)

sc-44816-SHmGene SilencingPuromycin0
(0)

NPC2 shRNA (m) Lentiviral Particles

sc-44816-VmGene SilencingPuromycin0
(0)

NPC1L1 siRNA (h)

sc-61225hGene SilencingN/A
2
(0)

NPC1L1 shRNA Plasmid (h)

sc-61225-SHhGene SilencingPuromycin
2
(0)

NPC1L1 shRNA (h) Lentiviral Particles

sc-61225-VhGene SilencingPuromycin
2
(0)

NPC1L1 siRNA (m)

sc-61226mGene SilencingN/A0
(0)

NPC1L1 shRNA Plasmid (m)

sc-61226-SHmGene SilencingPuromycin0
(0)

NPC1L1 shRNA (m) Lentiviral Particles

sc-61226-VmGene SilencingPuromycin0
(0)

NPC CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

NPC1 CRISPR/Cas9 KO Plasmid (h)

sc-403252Gene Knockouth0
(0)

NPC1 HDR Plasmid (h)

sc-403252-HDRHomology Directed Repairh0
(0)

NPC1 CRISPR/Cas9 KO Plasmid (m)

sc-421941Gene Knockoutm0
(0)

NPC1 HDR Plasmid (m)

sc-421941-HDRHomology Directed Repairm0
(0)

NPC1L1 CRISPR/Cas9 KO Plasmid (h)

sc-401741Gene Knockouth0
(0)

NPC CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

NPC1 Double Nickase Plasmid (h)

sc-403252-NICGene Knockouth0
(0)

NPC1 Double Nickase Plasmid (h2)

sc-403252-NIC-2Gene Knockouth0
(0)

NPC1 Double Nickase Plasmid (m)

sc-421941-NICGene Knockoutm0
(0)

NPC1 Double Nickase Plasmid (m2)

sc-421941-NIC-2Gene Knockoutm0
(0)

NPC1L1 Double Nickase Plasmid (h)

sc-401741-NICGene Knockouth0
(0)

NPC1L1 Double Nickase Plasmid (h2)

sc-401741-NIC-2Gene Knockouth0
(0)

NPC CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

NPC1 CRISPR Activation Plasmid (h)

sc-403252-ACTGene Activationh0
(0)

NPC2 CRISPR Activation Plasmid (h)

sc-402010-ACTGene Activationh0
(0)

NPC1L1 CRISPR Activation Plasmid (h)

sc-401741-ACTGene Activationh0
(0)