Date published: 2026-4-1

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NOMO3 Inhibitors

NOMO3 inhibitors constitute a specialized class of chemical compounds designed to selectively modulate the activity of the Nodal Modulator 3 (NOMO3) protein. The NOMO3 protein, while belonging to a larger family of nodal modulators, remains relatively understudied, and its exact functional roles within cellular processes are not yet fully elucidated. The inhibitors developed for NOMO3 exhibit a unique chemical structure, allowing them to interact selectively with specific binding sites on the NOMO3 protein, thereby influencing its molecular activities at the cellular level. The careful design of these inhibitors is essential for ensuring a high degree of specificity, minimizing unintended effects on other cellular components or proteins within the nodal modulator family.

The mechanism of action of NOMO3 inhibitors involves disrupting the normal functioning of the NOMO3 protein, potentially impacting cellular processes associated with its unique role. The selectivity of these inhibitors is crucial to prevent interference with other closely related nodal modulators or cellular pathways. As researchers delve into the intricacies of signaling pathways and nodal modulation, NOMO3 inhibitors serve as invaluable tools, allowing for the investigation of the precise molecular mechanisms governed by NOMO3. The study of this chemical class contributes to a deeper understanding of the role played by NOMO3 in cellular physiology, offering insights into its potential functions within the complex networks that regulate various cellular processes. Overall, the exploration of NOMO3 inhibitors provides a platform for advancing our understanding of the molecular landscape surrounding this less-explored member of the nodal modulator family.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

SB 431542

301836-41-9sc-204265
sc-204265A
sc-204265B
1 mg
10 mg
25 mg
$82.00
$216.00
$416.00
48
(1)

Inhibits ALK4/5/7 receptors, which may reduce NODAL signaling.

Methacycline Hydrochloride

3963-95-9sc-211806
sc-211806A
100 mg
1 g
$96.00
$693.00
(0)

Another ALK4/5/7 inhibitor that could potentially decrease NODAL pathway activity.

A 83-01

909910-43-6sc-203791
sc-203791A
10 mg
50 mg
$202.00
$811.00
16
(1)

Selectively inhibits ALK5, which is a receptor for NODAL, potentially reducing its signaling.

4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline

1062368-24-4sc-476297
5 mg
$240.00
(0)

Blocks ALK2/3/6 receptors and might indirectly affect NODAL signaling.

DMH-1

1206711-16-1sc-361171
sc-361171B
sc-361171A
sc-361171C
10 mg
25 mg
50 mg
100 mg
$213.00
$318.00
$632.00
$1047.00
2
(0)

Selectively inhibits ALK2, which could also modulate NODAL-related pathways.

SB-505124

694433-59-5sc-362794
sc-362794A
10 mg
50 mg
$327.00
$1377.00
2
(0)

Inhibits ALK4/5/7, possibly leading to a decrease in NODAL signaling.

A66

1166227-08-2sc-364394
sc-364394A
5 mg
50 mg
$255.00
$1455.00
(0)

Selective inhibitor of ALK4, which may impact NODAL signaling.

EW-7197

1352608-82-2sc-507465
5 mg
$345.00
(0)

A potent ALK4/5/7 inhibitor, potentially affecting NODAL pathway activity.

LDN-214117

1627503-67-6sc-507451
5 mg
$165.00
(0)

Inhibits ALK2 and may influence NODAL pathway signaling.

ALK5 Inhibitor II

446859-33-2sc-221234
sc-221234A
sc-221234B
sc-221234C
sc-221234D
sc-221234E
sc-221234F
1 mg
5 mg
10 mg
50 mg
100 mg
500 mg
1 g
$77.00
$153.00
$219.00
$663.00
$1248.00
$4382.00
$7850.00
8
(1)

Inhibits ALK5, which might lead to reduced NODAL signaling.