NOL10 Activators are compounds that can act either directly or indirectly to modulate the function or expression of NOL10 protein. They operate through distinct biochemical or cellular pathways, such as AMPK, NF-kappaB, and SIRT1 pathways, among others. The influence of these compounds on these pathways can lead to the activation of NOL10 by modulating its expression or its protein-protein interactions. For instance, chemicals like LY294002 and AICAR focus on AMPK activation, which is crucial for cellular energy metabolism and could therefore modulate NOL10 function through these AMPK-related pathways.
Other chemicals like BAY 11-7082 and SB216763 target NF-kappaB and Wnt signaling pathways, respectively. By modulating these pathways, they can influence the activity of NOL10, potentially enhancing its role in the cellular processes it is involved in. For example, an increase in NF-kappaB activity could lead to a change in NOL10 expression or activation, given that NOL10 is involved in various cellular processes including ribosome biogenesis and possibly gene regulation. Similarly, Wnt signaling activators can affect NOL10 function by possibly enhancing its protein-protein interactions within the Wnt pathway.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor that can lead to AMPK activation, potentially influencing NOL10 via AMPK-related pathways. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AMPK activator that affects cellular metabolism; can enhance NOL10 function by modulating AMPK signaling. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
SIRT1 activator that can influence NOL10 by impacting gene expression through SIRT1-modulated pathways. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
Inhibits IκBα phosphorylation, leading to NF-kappaB activation, which can indirectly affect NOL10 expression. | ||||||
Metformin-d6, Hydrochloride | 1185166-01-1 | sc-218701 sc-218701A sc-218701B | 1 mg 5 mg 10 mg | $286.00 $806.00 $1510.00 | 1 | |
AMPK activator that can influence NOL10 via AMPK pathways related to cellular metabolism. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
cAMP activator; can lead to PKA activation, potentially affecting NOL10 function via PKA-modulated pathways. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
HDAC inhibitor that can lead to chromatin remodeling, potentially affecting NOL10 function through gene expression. | ||||||
SB-216763 | 280744-09-4 | sc-200646 sc-200646A | 1 mg 5 mg | $70.00 $198.00 | 18 | |
GSK-3 inhibitor that can lead to the activation of β-catenin, potentially influencing NOL10 via Wnt-related pathways. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
ROCK inhibitor; can affect NOL10 by modulating Rho/ROCK signaling. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Affects multiple pathways including PI3K/AKT, which can influence NOL10 function. |