NNT-1/BSF-3 Inhibitors
NNT-1/BSF-3 inhibitors belong to a class of chemical compounds designed to target and modulate the activity of the Nicotinamide nucleotide transhydrogenase 1 (NNT-1) protein, also known as B-cell stimulatory factor 3 (BSF-3). NNT-1 is a mitochondrial enzyme that plays a pivotal role in cellular energy metabolism by participating in the transfer of electrons and protons across the mitochondrial inner membrane. This process is crucial for the generation of adenosine triphosphate (ATP), the primary energy currency of the cell. Inhibitors of NNT-1/BSF-3 are developed to interact with this enzyme, disrupting its function and influencing the balance of redox reactions within mitochondria.
These inhibitors are typically small molecules or compounds designed to bind to NNT-1/BSF-3, affecting its catalytic activity or its interactions with other components of the electron transport chain. By interfering with the electron and proton transfer process mediated by NNT-1, these inhibitors may impact the mitochondrial membrane and the overall production of ATP. Research into NNT-1/BSF-3 inhibitors can provide valuable insights into the regulation of cellular energy metabolism and the role of mitochondrial redox reactions in maintaining cellular homeostasis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid that may influence gene expression and suppress the activity of certain transcription factors. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenolic compound thought to modulate signal transduction pathways that can influence gene expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A bioactive compound from turmeric with the potential to modulate transcription factors and cytokine expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
A compound found in cruciferous vegetables that may affect gene expression by modifying histone acetylation and methylation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A derivative of vitamin A that regulates gene expression by activating nuclear receptors. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $69.00 $266.00 | 8 | |
An immunosuppressant that inhibits inosine monophosphate dehydrogenase, potentially affecting lymphocyte proliferation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A catechin from green tea that might alter transcription factors and signaling pathways affecting gene expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
An isoflavone that acts as a tyrosine kinase inhibitor and could modulate transcription and protein synthesis. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $99.00 $216.00 $510.00 | 11 | |
A flavonoid that may modulate cell signaling pathways influencing transcription and mRNA stability. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
A compound found in cruciferous vegetables that may alter estrogen metabolism and modulate gene transcription. | ||||||