NBPF14 inhibitors represent a unique category of chemical compounds designed to selectively modulate the activity of neuroblastoma breakpoint family member 14 (NBPF14) protein. The NBPF gene family has been associated with neurodevelopment, and individual members of this family are implicated in various cellular processes. NBPF14, specifically, is expressed in neural tissues and is thought to play a role in intricate molecular events shaping neuronal circuits. The inhibitors targeting NBPF14 possess a specific chemical structure that allows them to interact selectively with distinct binding sites on the NBPF14 protein, thereby influencing its molecular function at the cellular level.
The mechanism of action of NBPF14 inhibitors involves the disruption of normal cellular processes associated with NBPF14, potentially impacting neurodevelopmental pathways and other functions where NBPF14 is involved. The careful design of these inhibitors ensures a high level of specificity, minimizing unintended effects on other cellular components. As researchers explore the complexities of neurodevelopment and associated molecular pathways, NBPF14 inhibitors serve as valuable tools to unravel the intricate signaling cascades and molecular interactions involving NBPF14, contributing to a deeper understanding of its role in cellular physiology. The study of this chemical class may offer insights into the broader landscape of neurodevelopmental processes, shedding light on the molecular mechanisms governed by NBPF14 and its significance in the intricate cellular networks that shape the nervous system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
May inhibit DNA methylation, potentially leading to reactivation of silenced genes and altering the expression of NBPF14. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a histone deacetylase inhibitor, it can change the chromatin state and potentially affect NBPF14 expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A DNA methyltransferase inhibitor that could impact DNA methylation and gene expression, including NBPF14. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
This histone deacetylase inhibitor could broadly change gene expression patterns, possibly affecting NBPF14. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that may affect protein synthesis and gene expression, potentially influencing NBPF14 expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Interferes with DNA-dependent RNA polymerase, which could decrease the transcription of various genes, including NBPF14. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Binds to DNA and may inhibit the binding of transcription factors, possibly altering NBPF14 expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that could disrupt signaling pathways, potentially affecting NBPF14 gene regulation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Influences gene expression by interacting with nuclear receptors, potentially affecting NBPF14 expression. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $109.00 | 3 | |
May affect transcriptional regulation through its antagonism of mineralocorticoid receptors, potentially impacting NBPF14. | ||||||