Musclin Inhibitors
Musclin inhibitors refer to a class of compounds designed to inhibit the activity of the musclin protein, a muscle-derived hormone also known as osteocrin (OSTN). Musclin is predominantly expressed in skeletal muscle and bone, playing crucial roles in bone growth, muscle function, and metabolic regulation. Inhibitors of musclin would therefore be expected to impact these physiological processes.
Musclin inhibitors would include compounds that directly block the interaction of musclin with its target receptor or downstream signaling components. These inhibitors could bind to the active site of musclin, impeding it from interacting with its receptor and thus inhibiting its function. Musclin inhibitors would include compounds that can interfere with the expression or secretion of musclin. These could involve substances that block the transcription or translation of the OSTN gene, which encodes musclin, or compounds that block the secretion of the musclin protein from cells. For example, certain glucocorticoids could downregulate the expression of musclin in muscle and bone tissues, while some endoplasmic reticulum stress inhibitors could interfere with the secretion of musclin protein.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a polyphenol that has been shown to inhibit various proteins involved in the insulin signaling pathway, which Musclin is a part of. | ||||||
Troglitazone | 97322-87-7 | sc-200904 sc-200904B sc-200904A | 5 mg 10 mg 25 mg | $108.00 $200.00 $426.00 | 9 | |
Troglitazone is a thiazolidinedione that has been shown to affect various proteins involved in glucose metabolism, which Musclin is a part of. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
Pioglitazone is a thiazolidinedione that has been shown to affect various proteins involved in glucose metabolism, which Musclin is a part of. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
Rosiglitazone is a thiazolidinedione that has been shown to affect various proteins involved in glucose metabolism, which Musclin is a part of. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone is a corticosteroid that can affect various proteins involved in glucose metabolism, which Musclin is a part of. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride is known to affect the glycogen synthase kinase 3β (GSK3β) signaling pathway, potentially indirectly affecting Musclin. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor that can affect muscle protein synthesis and thereby potentially influence Musclin. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that can affect various proteins involved in the insulin signaling pathway, which Musclin is a part of. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a PI3K inhibitor that can affect various proteins involved in the insulin signaling pathway, which Musclin is a part of. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB 203580 is a p38 MAPK inhibitor that can affect various proteins involved in the insulin signaling pathway, which Musclin is a part of. | ||||||