MTRF1 Activators
The chemical class termed MTRF1 Activators includes compounds that can potentially modulate the activity or expression of MTRF1 through indirect mechanisms. These chemicals target a variety of signaling pathways and cellular processes, creating environments that can influence MTRF1. Metformin, through its action on AMPK, can modulate mitochondrial function and biogenesis, potentially impacting MTRF1 in the context of cellular metabolism. Resveratrol, activating SIRT1, and Rapamycin, inhibiting mTOR, affect mitochondrial dynamics and stress responses, pathways that are likely to intersect with MTRF1's role in mitochondrial translation.
Additionally, glycolysis inhibitors like 2-Deoxy-D-glucose and signaling modulators like Forskolin, which elevates cAMP levels, can create cellular conditions that indirectly affect MTRF1's function. Curcumin, with its broad effects on cellular signaling, including mitochondrial function, and LY294002, a PI3K inhibitor, can impact cellular processes potentially related to MTRF1. SB203580 and SP600125, affecting the MAPK pathway, Trichostatin A, a histone deacetylase inhibitor, and Y-27632, a ROCK inhibitor, could also modulate cellular environments in a manner that indirectly influences MTRF1. BAY 11-7082, by inhibiting NF-κB activation, might impact gene expression relevant to MTRF1's function.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Metformin-d6, Hydrochloride | 1185166-01-1 | sc-218701 sc-218701A sc-218701B | 1 mg 5 mg 10 mg | $286.00 $806.00 $1510.00 | 1 | |
An AMPK activator, influencing cellular energy metabolism. Metformin can modulate mitochondrial function and biogenesis, potentially affecting MTRF1 expression or activity as part of the mitochondrial stress response and cellular metabolism regulation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Activates SIRT1, which is involved in mitochondrial function and cellular stress responses. SIRT1 activation can lead to modulation of pathways potentially intersecting with MTRF1's function, potentially affecting its expression or activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, affecting cell growth and metabolism. Inhibition of mTOR signaling can indirectly influence mitochondrial dynamics and stress responses, potentially impacting MTRF1. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
A glycolysis inhibitor, inducing cellular energy stress. This alteration in energy metabolism can influence MTRF1 expression or activity as part of the cellular adaptation to energy stress. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels. Elevated cAMP can modulate signaling pathways potentially intersecting with MTRF1's function in mitochondrial translation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Known to modulate multiple signaling pathways, including those related to cellular stress and mitochondrial function. Curcumin's effects could indirectly influence MTRF1. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, impacting the AKT pathway. This modulation can influence MTRF1 indirectly by altering cellular survival, proliferation, and metabolism signals. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor, potentially affecting cellular response to stress or inflammation, thereby indirectly affecting MTRF1. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, part of the MAPK signaling pathways. By inhibiting JNK, it could indirectly influence MTRF1's function or expression by altering stress and inflammatory response signals. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor, potentially affecting gene expression patterns broadly, which could indirectly influence MTRF1. | ||||||