MTMR11 Activators constitute a specialized category of chemical compounds that have garnered attention in the field of molecular biology and cellular research. These activators are designed to modulate the activity of the MTMR11 gene, where MTMR11 stands for Myotubularin-Related Protein 11. This gene is a protein-coding element found in humans and is a member of the myotubularin-related (MTMR) family of proteins. MTMR proteins are known to play crucial roles in various cellular processes, including membrane trafficking, endocytosis, and the regulation of phosphoinositide signaling. MTMR11 Activators represent a group of molecules engineered to enhance or stimulate the expression and function of the MTMR11 gene, ultimately leading to an increase in the activity of the associated protein.
The mechanism of action of MTMR11 Activators typically involves their interaction with specific regulatory elements within the MTMR11 gene, such as promoter regions or enhancer sequences. These interactions facilitate the upregulation of gene transcription, resulting in heightened synthesis of the MTMR11 protein. MTMR11 is believed to play a role in dephosphorylating phosphoinositides, thereby influencing cellular membrane dynamics and vesicular trafficking. As researchers continue to explore the functions and potential implications of MTMR11 activation, the development and refinement of MTMR11 Activators offer the prospect of advancing our understanding of membrane biology, cellular dynamics, and the broader role of MTMR11 in cellular functionality and molecular pathways, potentially revealing novel aspects of cellular processes and their regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels and potentially influencing gene expression through cAMP response element-binding protein (CREB). | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid acts as a ligand for retinoic acid receptors, which can modulate gene transcription and potentially influence MTMR11 expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methyltransferase inhibitor, 5-Azacytidine can lead to demethylation and potentially upregulate MTMR11 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor that can alter chromatin structure and potentially increase MTMR11 gene expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium influences glycogen synthase kinase-3 (GSK-3) activity, which might affect various gene expressions including MTMR11 through the Wnt signaling pathway. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
As a histone deacetylase inhibitor, Sodium butyrate can induce epigenetic changes that might upregulate MTMR11 gene expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
This polyphenol from green tea can modulate various signaling pathways, potentially influencing MTMR11 gene expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates sirtuins and might influence gene expression patterns, including that of MTMR11. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate several signaling pathways and potentially affect the expression of various genes including MTMR11. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
This cAMP analog can activate cAMP-dependent pathways, potentially resulting in altered MTMR11 gene expression. | ||||||