Mtch2 Activators
Mtch2 Activators are a diverse set of chemical compounds that enhance the activity of Mtch2 through various mechanisms that promote mitochondrial health and function. Forskolin, by increasing intracellular cAMP, activates PKA, which may enhance Mtch2 function by influencing its phosphorylation state and mitochondrial localization. Resveratrol activates SIRT1 deacetylase, which may indirectly improve Mtch2 activity by optimizing mitochondrial protein function, while Pioglitazone, as a PPAR-gamma agonist, can enhance Mtch2's role in mitochondrial metabolism through alterations in gene transcription that affect fatty acid and glucose metabolism. Palmitic Acid, being a fatty acid substrate, can indirectly augment Mtch2 activity through the increased substrate availability for mitochondrial metabolism. Nicotinamide, as a precursor to NAD+, supports redox reactions and energy metabolism, which can enhance Mtch2 activity, and L-Carnitine, by promoting fatty acid transport into mitochondria, supports Mtch2's role in energy metabolism.
Additionally, Tauroursodeoxycholic Acid acts as a mitochondrial stabilizer, potentially boosting Mtch2 activity by ensuring mitochondrial integrity, and Spermidine, through the induction of autophagy, can improve the functional mitochondrial pool, indirectly enhancing Mtch2 activity. AICAR and Metformin, both activators of AMPK, promote mitochondrial biogenesis and efficient energy metabolism, which could lead to an indirect increase inMtch2 activity. Urolithin A, by inducing mitophagy, ensures the maintenance of a healthy mitochondrial population, which could indirectly increase the functional efficiency of Mtch2. Lastly, Alpha-lipoic acid, by acting as a cofactor for mitochondrial enzymes, supports the mitochondrial environment, potentially facilitating Mtch2's functional role within the mitochondria. These activators, through their targeted actions on different aspects of mitochondrial function and health, collectively enhance the activity of Mtch2, a protein implicated in the regulation of mitochondrial metabolism and apoptosis signaling.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Activates SIRT1, a deacetylase that modulates various mitochondrial proteins. SIRT1 activation can indirectly enhance Mtch2 function by deacetylating mitochondrial proteins, thus optimizing mitochondrial function and potentially facilitating Mtch2-mediated apoptosis signaling. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
As a PPAR-gamma agonist, it alters the transcription of genes involved in fatty acid storage and glucose metabolism, indirectly enhancing the functional role of Mtch2 in mitochondrial metabolism and apoptosis regulation due to altered substrate availability. | ||||||
Palmitic Acid | 57-10-3 | sc-203175 sc-203175A | 25 g 100 g | $114.00 $286.00 | 2 | |
As a free fatty acid, it can be transported into mitochondria where it is metabolized. Increased availability of fatty acids may enhance Mtch2 activity as it is implicated in the regulation of mitochondrial metabolism and apoptosis. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
A precursor of NAD+, which is essential in redox reactions and energy metabolism in mitochondria. Increased NAD+ levels can enhance Mtch2 activity by providing an optimized redox state and energy status within mitochondria. | ||||||
L-Carnitine | 541-15-1 | sc-205727 sc-205727A sc-205727B sc-205727C | 1 g 5 g 100 g 250 g | $23.00 $34.00 $79.00 $179.00 | 3 | |
Facilitates the transport of fatty acids into mitochondria for beta-oxidation. Enhanced fatty acid oxidation indirectly supports Mtch2 function by maintaining an efficient mitochondrial energy metabolism. | ||||||
Tauroursodeoxycholic Acid, Sodium Salt | 14605-22-2 | sc-281165 | 1 g | $644.00 | 5 | |
Acts as a mitochondrial stabilizer and has been shown to improve mitochondrial function. Enhanced mitochondrial health and function may indirectly augment Mtch2's role in mitochondrial metabolism. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $57.00 $607.00 $176.00 | ||
Induces autophagy and can lead to the selective degradation of damaged mitochondria (mitophagy), potentially enhancing the functional pool of Mtch2 by improving overall mitochondrial quality. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
Activates AMPK, which promotes mitochondrial biogenesis and energy homeostasis. Activation of AMPK could indirectly enhance Mtch2 activity by increasing the number of mitochondria and therefore the potential functional sites for Mtch2. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Activates AMPK, which improves mitochondrial function and may indirectly enhance Mtch2 activity by promoting a more efficient energy metabolism within mitochondria. | ||||||
Urolithin A | 1143-70-0 | sc-475514 sc-475514A sc-475514B sc-475514C | 25 mg 100 mg 1 g 5 g | $204.00 $459.00 $714.00 $1224.00 | 10 | |
Induces mitophagy, thus improving the health of mitochondria and potentially enhancing Mtch2 activity by ensuring a higher quality of functional mitochondria. | ||||||