The chemical class of mSHMT Activators includes compounds that can indirectly influence mSHMT function through their involvement in the one-carbon metabolism pathway, cofactor supplementation, and regulation of substrate availability. mSHMT, being central to amino acid metabolism and one-carbon transfer, is sensitive to changes in cofactor levels and substrate availability.
Compounds such as Folic Acid, Vitamin B6, and Methotrexate, by influencing folate metabolism, could indirectly affect mSHMT activity. Folic acid and vitamin B6 serve as cofactors for mSHMT, enhancing its enzymatic function, while methotrexate, by inhibiting folate metabolism, could have indirect effects on mSHMT activity. Other compounds like S-Adenosylmethionine, Betaine, and Choline, which are involved in methyl group transfers and the methionine cycle, can also indirectly influence mSHMT activity. Homocysteine levels can impact methylation pathways, thereby affecting mSHMT.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Folic Acid | 59-30-3 | sc-204758 | 10 g | $73.00 | 2 | |
As a cofactor for mSHMT, it can enhance its enzymatic activity. | ||||||
Pyridoxine Hydrochloride | 58-56-0 | sc-219674 | 10 mg | $42.00 | ||
Pyridoxine, a form of vitamin B6, is a cofactor for mSHMT, potentially enhancing its function. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
An inhibitor of dihydrofolate reductase, can influence folate metabolism, indirectly affecting mSHMT activity. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $184.00 $668.00 | 2 | |
Involved in methyl group transfers, can influence methylation reactions where mSHMT is involved. | ||||||
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $31.00 $41.00 $56.00 $163.00 $337.00 $592.00 | 2 | |
Acts as a methyl donor in the methionine cycle, potentially affecting mSHMT activity. | ||||||
Choline base solution | 123-41-1 | sc-239545 | 100 ml | $79.00 | ||
As a precursor to betaine, it indirectly influences mSHMT activity through the methionine cycle. | ||||||
Homocysteine | 6027-13-0 | sc-507315 | 250 mg | $195.00 | ||
Elevated levels can affect methylation pathways, potentially impacting mSHMT function. | ||||||
Riboflavin | 83-88-5 | sc-205906 sc-205906A sc-205906B | 25 g 100 g 1 kg | $41.00 $112.00 $525.00 | 3 | |
As a cofactor in various enzymatic reactions, it may influence pathways where mSHMT is involved. | ||||||
Glycine | 56-40-6 | sc-29096A sc-29096 sc-29096B sc-29096C | 500 g 1 kg 3 kg 10 kg | $41.00 $71.00 $112.00 $357.00 | 15 | |
As a product of mSHMT reaction, its levels can influence mSHMT activity through feedback mechanisms. | ||||||
L-Serine | 56-45-1 | sc-397670 sc-397670A sc-397670B sc-397670C sc-397670D | 1 g 100 g 1 kg 5 kg 10 kg | $20.00 $133.00 $546.00 $1224.00 $2040.00 | ||
As a substrate for mSHMT, increased levels could enhance its activity. | ||||||