Molecular structure of Glycine, CAS Number: 56-40-6
Glycine (CAS 56-40-6)
See product citations (15)
Alternate Names:
Glycine also known as Aminoacetic acid; Aminoethanoic acid; Glycocoll; glicina; TRIS-TRICINE BUFFER; TRIS-GLYCINE, Amitone; Athenon; Glicoamin; Glykokoll; Glycolixir; Glycosthene; BLOTTING BUFFER
Application:
Glycine is a widely used buffer used for polyacrylamide gel electrophoresis, Western blots and for the preparation of TG buffers
CAS Number:
56-40-6
Purity:
≥98%
Molecular Weight:
75.07
Molecular Formula:
C2H5NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Glycine is widely used as a buffer for a variety of immunological applications. Glycine is frequently used in the preparation of TG Buffers (Tris-Glycine sc-296648) where the buffer is used as a running and/or transfer buffer for polyacrylamide gel electrophoresis and western blotting. Glycine (100 mM, pH 2.0-2.5 sc-295018) is also used as an eluent in column chromatography. Glycine has been reported for use in the enzymatic determination of lactate using lactic dehydrogenase. Glycine has also been use for the preparation of gelatin composites scaffold. Glycine, a non-essential amino acid, plays a role in proteins and various biological processes. It is a simple molecule made up of one carbon, two hydrogen atoms, and one oxygen atom. Glycine is a small, polar molecule that readily dissolves in water and is abundant in numerous biological fluids. As a significant neurotransmitter, especially in the central nervous system, it contributes to muscle contraction regulation, memory formation, and learning. Moreover, it serves as a precursor to vital molecules like porphyrins, purines, and heme.
Glycine (CAS 56-40-6) References
- Glycine modulators in schizophrenia. | Javitt, DC. 2002. Curr Opin Investig Drugs. 3: 1067-72. PMID: 12186269
- A role for glycine in the gating of plant NMDA-like receptors. | Dubos, C., et al. 2003. Plant J. 35: 800-10. PMID: 12969432
- Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia. | Kikuchi, G., et al. 2008. Proc Jpn Acad Ser B Phys Biol Sci. 84: 246-63. PMID: 18941301
- Glycine amides as PPARalpha agonists. | Urbahns, K., et al. 2010. Bioorg Med Chem Lett. 20: 3376-9. PMID: 20452212
- Glycine insertion makes yellow fluorescent protein sensitive to hydrostatic pressure. | Watanabe, TM., et al. 2013. PLoS One. 8: e73212. PMID: 24014139
- Glycine improves biochemical and biomechanical properties following inflammation of the achilles tendon. | Vieira, CP., et al. 2015. Anat Rec (Hoboken). 298: 538-45. PMID: 25156668
- Glycine Substitutions in Collagen Heterotrimers Alter Triple Helical Assembly. | Clements, KA., et al. 2017. Biomacromolecules. 18: 617-624. PMID: 28098982
- [The effect of nutrition on the metabolism of glycine]. | Petzke, KJ. and Albrecht, V. 1987. Nahrung. 31: 157-72. PMID: 3302715
- [The effect of oral administration of glycine on metabolism]. | Petzke, KJ., et al. 1987. Nahrung. 31: 207-15. PMID: 3302716
- Glycine 236 in the Lower Hinge Region of Human IgG1 Differentiates FcγR from Complement Effector Function. | Brinkhaus, M., et al. 2020. J Immunol. 205: 3456-3467. PMID: 33188070
- Inward-facing glycine residues create sharp turns in β-barrel membrane proteins. | Zhang, Z., et al. 2021. Biochim Biophys Acta Biomembr. 1863: 183662. PMID: 34097860
- Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. | Towbin, H., et al. 1979. Proc Natl Acad Sci U S A. 76: 4350-4. PMID: 388439
- Cleavage of structural proteins during the assembly of the head of bacteriophage T4. | Laemmli, UK. 1970. Nature. 227: 680-5. PMID: 5432063
- Neurotransmission by neurons that use serotonin, noradrenaline, glutamate, glycine, and gamma-aminobutyric acid in the normal and injured spinal cord. | Shapiro, S. 1997. Neurosurgery. 40: 168-76; discussion 177. PMID: 8971839
- Glycine. | Hall, JC. 1998. JPEN J Parenter Enteral Nutr. 22: 393-8. PMID: 9829614
Inhibitor of:
Amelogenin, GLYATL2, LYZL4, Olfr788, and Prothrombin.Activator of:
α-2 antiplasmin, βB3-crystallin, 4930412D23Rik, Adenovirus-5 hexon, AGAT, AGT1, AGXT, AIDA-1, ALAS-E, ALAS-H, AMT, ARSA, BAAT, Blue Carrier Protein-sterile, CatSperγ, CD300C, Cerebellin 2, COL12A1, COL13A1, COL14A1, COL18A1, COL20A1, COL22A1, COL23A1, COL28A1, COL4A3, COL4A5, COL4A6, COL5A2, COL6A2, COL9A2, Collagen Type IV, Collagen Type IV-α2, Collagen Type XV, CPA5, CRTAP, cyt19, DAAO, DPEP2, DSPG3, dUTPase, EAAT1, EF-1 β, ERC2, EXT1, FGF-7, Fibulin-4, GAMT, GART, Gatm, Gephyrin, GGCT, GGL, GLYAT, GLYATL1, GLYATL2, GLYATL3, GlyR α1 (GLRA1), GlyR β, GOT1L1, GRIN2, GRINA, GSH-1, Gtlf3b, HEM1, HLA-HB1, HNK-1ST, IgG3, Keratin 82, KRTAP17-1, KY peptidase, L-serine dehydratase, LEPREL1, LEPREL2, LIN-7, LOXL3, LRRC8D, LRRTM1, MARS2, MBL-A, MetRS, mSHMT, MTHFD2L, MTR, NAALAD2, NAALADL1, NAALADL2, Neurexophilin-4, NGL-1, NMDA, NMDAε1, NMDAε3, NMDAζ1, NR3B, Olfr517, Olfr518, Olr1104, OR5F1, PAT2, PCPE-2, Pepsin A, PGCP, PGDH, Porphobilinogen synthase, PRMT2, Procollagen Type III, PRPS2, PRTFDC1, PSD2, PSPH, QCR10, RFPL4, Ribosomal Protein L31, Ribosomal Protein L41, Ribosomal Protein S12, SAHH, SCGN, Selenium, SLC6A14, SLC6A15, SLC6A19, SLITRK4, SRP14, STEP, SULT6B1, T1R3, THNSL2, Transcobalamin II, Trypsin-3, UROS, V1RD13, V1RD6, V5-Probe, Vmn1r184, Vmn2r100, Vmn2r102, Vmn2r104, Vmn2r11, VSTM3, X11γ, and ZADH2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glycine, 500 g | sc-29096A | 500 g | $40.00 | |||
Glycine, 1 kg | sc-29096 | 1 kg | $70.00 | |||
Glycine, 3 kg | sc-29096B | 3 kg | $110.00 | |||
Glycine, 10 kg | sc-29096C | 10 kg | $350.00 |