Molecular structure of L-Serine, CAS Number: 56-45-1
L-Serine (CAS 56-45-1)
Alternate Names:
(S)-2-Amino-3-hydroxypropionic acid
Application:
L-Serine is L-Serine is a D-amino acid synthesis reagent
CAS Number:
56-45-1
Molecular Weight:
105.09
Molecular Formula:
C3H7NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
L-Serine is a D-amino acid synthesis reagent. L-Serine is also the precursor of glycine by serine hydroxymethyltransferase. It is used in the synthesis of purines and pyrimidines as antibacterial agents. In vitro, it is used to study the structure and functions of enzymes and other biological molecules.
L-Serine (CAS 56-45-1) References
- L-serine in disease and development. | de Koning, TJ., et al. 2003. Biochem J. 371: 653-61. PMID: 12534373
- Serine-deficiency syndromes. | de Koning, TJ. and Klomp, LW. 2004. Curr Opin Neurol. 17: 197-204. PMID: 15021249
- An essential role for de novo biosynthesis of L-serine in CNS development. | Furuya, S. 2008. Asia Pac J Clin Nutr. 17 Suppl 1: 312-5. PMID: 18296366
- Roles of l-serine and sphingolipid synthesis in brain development and neuronal survival. | Hirabayashi, Y. and Furuya, S. 2008. Prog Lipid Res. 47: 188-203. PMID: 18319065
- L-serine synthesis in the central nervous system: a review on serine deficiency disorders. | Tabatabaie, L., et al. 2010. Mol Genet Metab. 99: 256-62. PMID: 19963421
- L-Serine overproduction with minimization of by-product synthesis by engineered Corynebacterium glutamicum. | Zhu, Q., et al. 2015. Appl Microbiol Biotechnol. 99: 1665-73. PMID: 25434811
- L-Serine: a Naturally-Occurring Amino Acid with Therapeutic Potential. | Metcalf, JS., et al. 2018. Neurotox Res. 33: 213-221. PMID: 28929385
- Microbial Production of l-Serine from Renewable Feedstocks. | Zhang, X., et al. 2018. Trends Biotechnol. 36: 700-712. PMID: 29500004
- L-serine supplementation lowers diabetes incidence and improves blood glucose homeostasis in NOD mice. | Holm, LJ., et al. 2018. PLoS One. 13: e0194414. PMID: 29543915
- L-serine: a neglected amino acid with a potential therapeutic role in diabetes. | Holm, LJ. and Buschard, K. 2019. APMIS. 127: 655-659. PMID: 31344283
- l-Serine Lowers the Inflammatory Responses during Pasteurella multocida Infection. | He, F., et al. 2019. Infect Immun. 87: PMID: 31570555
- l-Serine links metabolism with neurotransmission. | Maugard, M., et al. 2021. Prog Neurobiol. 197: 101896. PMID: 32798642
- Glycolysis-derived L-serine levels versus PHGDH expression in Alzheimer's disease. | Bonvento, G., et al. 2022. Cell Metab. 34: 654-655. PMID: 35508106
- Effects of l-Serine on Macrolide Resistance in Streptococcus suis. | Wu, T., et al. 2022. Microbiol Spectr. 10: e0068922. PMID: 35867475
- L-serine production by a methylotroph and its related enzymes. | Izumi, Y., et al. 1993. Appl Microbiol Biotechnol. 39: 427-32. PMID: 7763921
Inhibitor of:
ASCT1, ASPG, PGDH, PIG-K, PSAT1, PSPH, and SLC43A2.Activator of:
AGPS, AGXT2, Akp-3, AMT, Asparagine synthetase, ASPG, CHPT1, COL23A1, COL6A2, COL9A2, cyt19, DSPG3, EG629667, Ethanolamine kinase 2, FADS7_Degs1, GFRP, GlyT2, GNPAT, GRHPR, HTF9C, LASS1, LASS5, MARS2, MAT III, mSHMT, MTHFD2L, ORMDL3, PAT2, PE, PGD synthase, PGDH, PIG-F, PM20D1, PSS1, PSS2, PSTK, SAHH, Salmonella flagella, SerRSmt, SLA/LP, SLC7A9, SNAT3, SPTLC1, SPTLC2, TDE1, THNSL2, TS, and YLAT1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Serine, 1 g | sc-397670 | 1 g | $20.00 | |||
L-Serine, 100 g | sc-397670A | 100 g | $130.00 | |||
L-Serine, 1 kg | sc-397670B | 1 kg | $535.00 | |||
L-Serine, 5 kg | sc-397670C | 5 kg | $1200.00 | |||
L-Serine, 10 kg | sc-397670D | 10 kg | $2000.00 |