MRM1 Inhibitors
MRM1 inhibitor compounds such as Brefeldin A and LY294002 disrupt intracellular trafficking and phosphoinositide 3-kinase (PI3K) signaling, respectively, pathways that can be critical for the localization and function of MRM1 within the cell. PD98059 and Staurosporine target the MAP kinase pathway and a wide range of kinases, respectively, and are capable of modulating signaling cascades that could intersect with the activity of MRM1. Rapamycin, an inhibitor of the mammalian target of rapamycin (mTOR), can alter crucial cell growth and survival signals, potentially affecting the context within which MRM1 operates.
Furthermore, NF-κB Activation Inhibitor and SB431542 can modulate inflammation and TGF-β signaling pathways, which may play a part in regulating MRM1's activity or stability. ICG-001 and SP600125 target the Wnt/β-catenin and JNK signaling pathways, respectively, offering additional means by which the cellular environment of MRM1 can be influenced, potentially affecting its regulation or function.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Inhibits histone deacetylases (HDACs), leading to changes in chromatin structure and gene expression, which can modulate MRM1 expression or function. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, altering DNA methylation patterns and gene expression, including genes related to MRM1. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
A proteasome inhibitor, potentially increasing the half-life of proteins that regulate MRM1 or its cellular context. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Disrupts protein trafficking by inhibiting the ADP-ribosylation factor, which can affect MRM1's subcellular localization or stability. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor, altering signaling pathways that may intersect with MRM1's regulatory network. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor of MEK, which may affect the MAPK/ERK pathway and potentially modulate MRM1's activity or expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, influencing cell growth and survival pathways that could involve MRM1. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A broad-spectrum kinase inhibitor that can modulate various signaling pathways, possibly affecting MRM1's function. | ||||||
CAY10512 | 139141-12-1 | sc-205237 sc-205237A | 10 mg 100 mg | $68.00 $550.00 | ||
Inhibits NF-κB signaling, which can alter the expression of genes regulated by MRM1 or its regulatory proteins. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
An inhibitor of the TGF-β receptor, potentially affecting signaling pathways that intersect with those involving MRM1. | ||||||