MrgA7 Inhibitors
MrgA7 Inhibitors represent a diverse group of chemicals targeting various cellular pathways associated with the MrgA7 protein. These inhibitors exert their effects through different mechanisms, such as modulating kinases (A-769662, SB-203580, LY294002, U0126, PD98059), inhibiting phosphatases (Wortmannin), and impacting key signaling cascades like mTOR (Rapamycin) and JNK (SP600125). Additionally, inhibitors like BAY 11-7082 target transcription factors (NF-κB), influencing gene expression related to MrgA7. The TGF-β receptor inhibitor (SB-431542) and GSK-3 inhibitor (SB-216763) showcase the diversity of pathways that can indirectly regulate MrgA7. AG-490, a JAK2 inhibitor, highlights the potential modulation of JAK/STAT pathways connected to MrgA7. This chemical class provides a toolkit for researchers to explore and manipulate cellular processes associated with MrgA7, offering valuable insights into its regulatory mechanisms.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $184.00 $741.00 $1076.00 $3417.00 $5304.00 | 23 | |
A-769662 is an AMP-activated protein kinase (AMPK) activator that indirectly inhibits MrgA7 via AMPK pathways. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB-203580 acts as a p38 mitogen-activated protein kinase (MAPK) inhibitor, potentially affecting MrgA7 pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 inhibits phosphatidylinositol 3-kinases (PI3Ks), influencing downstream processes related to MrgA7. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is a MEK1/2 inhibitor, disrupting the MAPK/ERK pathway and potentially interfering with MrgA7 activation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin inhibits PI3Ks, impacting signaling cascades that may modulate MrgA7 activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor, affecting pathways that could indirectly regulate MrgA7. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 inhibits MEK1, potentially disrupting MAPK signaling pathways associated with MrgA7. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor that may influence c-Jun N-terminal kinase pathways connected to MrgA7. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
BAY 11-7082 inhibits NF-κB, impacting transcriptional regulation and potentially modulating MrgA7 expression. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
SB-431542 is a TGF-β receptor inhibitor, affecting TGF-β pathways that could indirectly regulate MrgA7. | ||||||