MLLT6 Activators
MLLT6 Activators represents a conjectural category of compounds that might modulate the expression or activity of MLLT6 through indirect mechanisms by engaging with diverse biochemical pathways. These chemicals generally function by altering the epigenetic landscape, such as DNA methylation and histone modification, which can lead to changes in chromatin structure and gene expression. Such changes in the epigenetic state of cells can result in the upregulation of a multitude of genes, potentially including MLLT6. Compounds like 5-Azacytidine and SAHA can demethylate DNA or modify histone acetylation, respectively, thus modifying the transcriptional accessibility of various genes.
In the second group are those that engage specific signaling pathways or enzyme functions that can lead to altered cellular states and indirectly affect the expression of genes like MLLT6. For example, Forskolin, by elevating cAMP levels, might stimulate a signaling cascade that culminates in transcriptional changes. Similarly, Genistein can modulate signaling pathways that ultimately influence gene expression profiles. The rationale for considering such compounds as putative MLLT6 Activators is rooted in the notion that the perturbation of cellular regulatory mechanisms can create a conducive environment for the expression of certain genes, including MLLT6, by influencing transcription factors, co-factors, and the general transcriptional machinery.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A cytidine analog used as a DNA methyltransferase inhibitor, which can lead to hypomethylation of DNA and potentially upregulate genes that are otherwise silenced, including potentially MLLT6. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
A histone deacetylase inhibitor, which leads to an open chromatin state and could enhance the transcription of various genes including MLLT6. | ||||||
EPZ6438 | 1403254-99-8 | sc-507456 | 1 mg | $66.00 | ||
A selective inhibitor of EZH2, which can result in reduced histone methylation and potentially increased expression of genes like MLLT6. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Activates retinoic acid receptors, influencing gene expression patterns in cell differentiation and proliferation pathways which may upregulate MLLT6 indirectly. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels and thereby potentially enhancing the transcription of a wide range of genes, possibly including MLLT6. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
A tyrosine kinase inhibitor known to modulate several cellular processes, possibly affecting MLLT6 expression through altered signaling pathways. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Another histone deacetylase inhibitor that could lead to chromatin remodeling and upregulation of gene expression, including MLLT6. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
A non-nucleoside DNA methyltransferase inhibitor, which could lead to upregulation of genes that are silenced by DNA methylation, potentially including MLLT6. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
A benzamide histone deacetylase inhibitor, potentially increasing expression of genes through an open chromatin configuration that could include MLLT6. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibitor | 935693-62-2 free base | sc-202651 | 5 mg | $148.00 | 4 | |
A diazepin-quinazolin-amine derivative that inhibits G9a and GLP histone methyltransferases, potentially altering the expression of genes such as MLLT6. | ||||||