Mitoferrin Activators
Mitoferrin activators represent a diverse array of chemicals that converge on the central theme of modulating mitochondrial function and cellular iron homeostasis. By fine-tuning the cellular milieu, these compounds set the stage for the potential activation of Mitoferrin, the transporter responsible for shuttling iron into the mitochondria. Iron chelators like DFP underscore the inherent link between cellular iron levels and Mitoferrin activity. By sequestering iron, they create an iron-depleted environment, which can boost the activity of Mitoferrin in an effort to maintain iron equilibrium within cells.
On the other hand, chemicals that directly affect mitochondrial functions, such as FCCP, CCCP, and Oligomycin, tap into the intricate balance of mitochondrial energetics, emphasizing the role of the mitochondria not just as energy producers but also as iron hubs. Additionally, chemicals like Rapamycin and Bafilomycin A1 highlight the interconnected pathways that weave the fabric of cellular iron homeostasis, from mTOR signaling to lysosomal iron processing.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $94.00 $355.00 | 46 | |
Uncouples mitochondrial oxidative phosphorylation, affecting mitochondrial functions and possibly Mitoferrin activity. | ||||||
Ferrous Sulfate (Iron II Sulfate) Heptahydrate | 7782-63-0 | sc-211505 sc-211505A | 250 g 500 g | $73.00 $109.00 | ||
Provides iron, potentially boosting Mitoferrin activity to facilitate iron import into mitochondria. | ||||||
Iron(III) citrate | 3522-50-7 | sc-286019 sc-286019A | 100 g 250 g | $46.00 $87.00 | ||
An iron source that can influence iron homeostasis and thereby potentially impact Mitoferrin activity. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $259.00 | 41 | |
Inhibits mitochondrial electron transport, potentially modulating Mitoferrin activity in response to altered iron needs. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Increases intracellular calcium, potentially influencing Mitoferrin via altered mitochondrial dynamics. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR, which can affect cellular iron homeostasis and potentially Mitoferrin activity. | ||||||
Carbonyl Cyanide m-Chlorophenylhydrazone | 555-60-2 | sc-202984A sc-202984 sc-202984B | 100 mg 250 mg 500 mg | $77.00 $153.00 $240.00 | 8 | |
Another uncoupler, potentially influencing mitochondrial iron dynamics and Mitoferrin activity. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
Inhibits ATP synthase, which can alter mitochondrial function and influence Mitoferrin activity. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $98.00 $255.00 $765.00 $1457.00 | 280 | |
Inhibits vacuolar ATPase, impacting lysosomal iron release and potentially influencing Mitoferrin activity. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
Inhibits mitochondrial permeability transition, potentially affecting Mitoferrin activity. | ||||||