mGluR-5 Inhibitors
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Items 11 to 20 of 22 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(S)-MCPG | 150145-89-4 | sc-202329 sc-202329A | 5 mg 25 mg | $143.00 $945.00 | ||
(S)-MCPG selectively targets the mGluR-5 receptor, functioning as a competitive antagonist with a distinct binding affinity. Its stereochemistry facilitates unique interactions with receptor sites, enhancing specificity through tailored electrostatic and van der Waals forces. The compound exhibits notable reaction kinetics, characterized by a swift equilibrium between bound and unbound states, which can significantly impact intracellular signaling pathways and neuronal communication dynamics. | ||||||
PHCCC | sc-361292 sc-361292A | 10 mg 50 mg | $145.00 $615.00 | |||
PHCCC is a selective allosteric modulator of the mGluR-5 receptor, enhancing receptor activity through unique conformational changes. Its structural features promote specific interactions with the receptor's allosteric site, leading to altered signaling cascades. The compound exhibits a distinct kinetic profile, allowing for prolonged receptor engagement and modulation of downstream effects. This behavior influences synaptic plasticity and neuronal excitability, showcasing its intricate role in cellular communication. | ||||||
(RS)-α-Methyl-3-carboxy-4-hydroxyphenylglycine | sc-222264 | 5 mg | $60.00 | |||
(RS)-α-Methyl-3-carboxy-4-hydroxyphenylglycine acts as a selective modulator of the mGluR-5 receptor, engaging in unique hydrogen bonding and hydrophobic interactions that stabilize receptor conformation. Its distinct molecular architecture facilitates specific binding dynamics, resulting in nuanced alterations in intracellular signaling pathways. The compound's interaction kinetics allow for a tailored modulation of receptor activity, impacting synaptic transmission and neuronal network behavior. | ||||||
SIB 1893 | 6266-99-5 | sc-203262 sc-203262A | 10 mg 50 mg | $138.00 $587.00 | ||
SIB 1893 is a selective allosteric modulator of the mGluR-5 receptor, characterized by its ability to induce conformational changes that enhance receptor sensitivity to glutamate. Its unique structural features promote specific electrostatic interactions, influencing downstream signaling cascades. The compound exhibits distinct binding kinetics, allowing for a fine-tuned regulation of receptor activity, which can lead to differential modulation of synaptic plasticity and neuronal excitability. | ||||||
SIB 1757 | 31993-01-8 | sc-204277 sc-204277A | 10 mg 50 mg | $91.00 $403.00 | ||
SIB 1757 acts as a selective modulator of the mGluR-5 receptor, distinguished by its capacity to stabilize receptor conformations that favor ligand binding. Its unique molecular architecture facilitates specific hydrophobic interactions, which play a crucial role in altering receptor dynamics. The compound's reaction kinetics are notable for their rapid onset and prolonged effects, enabling nuanced control over intracellular signaling pathways and influencing synaptic transmission mechanisms. | ||||||
(S)-4C3H-PG | 85148-82-9 | sc-203249 sc-203249A | 1 mg 5 mg | $30.00 $123.00 | ||
(S)-4C3H-PG is a selective modulator of the mGluR-5 receptor, characterized by its ability to induce distinct allosteric changes that enhance receptor sensitivity to endogenous ligands. Its unique structural features promote specific electrostatic interactions, which are pivotal in modulating receptor activity. The compound exhibits a remarkable affinity for binding sites, leading to altered signaling cascades and influencing downstream cellular responses with precision. | ||||||
(S)-HexylHIBO | 334887-48-8 | sc-203691 sc-203691A | 10 mg 50 mg | $169.00 $793.00 | ||
(S)-HexylHIBO is a potent allosteric modulator of the mGluR-5 receptor, distinguished by its unique hydrophobic interactions that stabilize receptor conformation. This compound facilitates enhanced receptor activation through specific binding dynamics, promoting nuanced signaling pathways. Its kinetic profile reveals a rapid onset of action, allowing for fine-tuning of receptor responses. The distinct molecular architecture of (S)-HexylHIBO contributes to its selective engagement with mGluR-5, influencing cellular communication effectively. | ||||||
ADX-47273 | 851881-60-2 | sc-364397 sc-364397A | 5 mg 10 mg | $433.00 $764.00 | ||
ADX-47273 is a selective allosteric modulator of the mGluR-5 receptor, characterized by its unique ability to induce conformational changes that enhance receptor signaling. Its molecular design allows for specific interactions with key amino acid residues, promoting a distinct signaling cascade. The compound exhibits a favorable kinetic profile, enabling swift modulation of receptor activity, which can lead to intricate alterations in synaptic transmission and neuronal plasticity. | ||||||
S-(+)-CBPG | sc-222268 sc-222268A | 1 mg 5 mg | $35.00 $133.00 | |||
S-(+)-CBPG is a potent allosteric modulator of the mGluR-5 receptor, distinguished by its capacity to stabilize receptor conformations that favor enhanced signaling. This compound engages in specific hydrogen bonding and hydrophobic interactions with critical binding sites, facilitating unique downstream signaling pathways. Its rapid binding kinetics allow for dynamic modulation of receptor activity, influencing synaptic dynamics and neuronal communication in a nuanced manner. | ||||||
A 841720 | 869802-58-4 | sc-203792 sc-203792A | 10 mg 50 mg | $172.00 $726.00 | ||
A 841720 acts as a selective modulator of the mGluR-5 receptor, characterized by its ability to induce conformational changes that promote receptor activation. This compound exhibits unique electrostatic interactions with key amino acid residues, enhancing receptor affinity and selectivity. Its distinct reaction kinetics enable a swift onset of action, allowing for precise regulation of intracellular signaling cascades. The compound's structural features contribute to its specificity, influencing receptor dynamics and functional outcomes. | ||||||