Date published: 2025-10-14

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mGluR-5 Antibodies

Santa Cruz Biotechnology delivers a wide array of mGluR-5 monoclonal antibodies for investigating metabotropic glutamate receptor 5. mGluR-5 Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). mGluR-5 plays a critical role in synaptic transmission and plasticity, influencing cognitive functions such as learning and memory. Dysregulation of mGluR-5 has been implicated in several neurological disorders, including schizophrenia and fragile X syndrome, making it a significant target for therapeutic intervention. Understanding the function and signaling pathways of mGluR-5 is essential for advancing research in neurobiology and developing potential treatments. Research utilizing mGluR-5 monoclonal antibodies has revealed important insights into receptor localization, expression patterns, and molecular interactions. Investigating mGluR-5 signaling cascades has enhanced our understanding of synaptic plasticity mechanisms and their role in learning and memory formation. The specificity and reliability of Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific knowledge in neuroscience and contribute to the development of therapeutic strategies.

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mGluR-5 Antibodies

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mGluR-5 Antibody (1B3)

sc-293442mouse IgG2a κ419-518 (h)WB, IP, ELISAm, r, h
1
(3)

mGluR-5 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

mGluR-5 CRISPR/Cas9 KO Plasmid (h)

sc-401460hGene KnockoutGFP0
(0)

mGluR-5 HDR Plasmid (h)

sc-401460-HDRhHomology Directed RepairPuromycin0
(0)

mGluR-5 Double Nickase Plasmid (h)

sc-401460-NIChGene KnockoutPuromycin0
(0)

mGluR-5 Double Nickase Plasmid (h2)

sc-401460-NIC-2hGene KnockoutPuromycin0
(0)

mGluR-5 CRISPR/Cas9 KO Plasmid (m)

sc-430797mGene KnockoutGFP0
(0)

mGluR-5 HDR Plasmid (m)

sc-430797-HDRmHomology Directed RepairPuromycin0
(0)

mGluR-5 Double Nickase Plasmid (m)

sc-430797-NICmGene KnockoutPuromycin0
(0)

mGluR-5 Double Nickase Plasmid (m2)

sc-430797-NIC-2mGene KnockoutPuromycin0
(0)

mGluR-5 CRISPR Activation Products

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mGluR-5 CRISPR Activation Plasmid (h)

sc-401460-ACThGene ActivationPuro, Blast, Hygro0
(0)

mGluR-5 CRISPR Activation Plasmid (h2)

sc-401460-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

mGluR-5 Lentiviral Activation Particles (h)

sc-401460-LAChGene ActivationPuro, Blast, Hygro0
(0)

mGluR-5 Lentiviral Activation Particles (h2)

sc-401460-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

mGluR-5 CRISPR Activation Plasmid (m)

sc-430797-ACTmGene ActivationPuro, Blast, Hygro0
(0)

mGluR-5 CRISPR Activation Plasmid (m2)

sc-430797-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

mGluR-5 Lentiviral Activation Particles (m)

sc-430797-LACmGene ActivationPuro, Blast, Hygro0
(0)

mGluR-5 Lentiviral Activation Particles (m2)

sc-430797-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

mGluR-5 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

mGluR-5 siRNA (h)

sc-61034hGene SilencingN/A0
(0)

mGluR-5 shRNA Plasmid (h)

sc-61034-SHhGene SilencingPuromycin0
(0)

mGluR-5 shRNA (h) Lentiviral Particles

sc-61034-VhGene SilencingPuromycin0
(0)

mGluR-5 siRNA (m)

sc-61035mGene SilencingN/A
1
(0)

mGluR-5 shRNA Plasmid (m)

sc-61035-SHmGene SilencingPuromycin
1
(0)

mGluR-5 shRNA (m) Lentiviral Particles

sc-61035-VmGene SilencingPuromycin
1
(0)

mGluR-5 siRNA (r)

sc-270671rGene SilencingN/A0
(0)

mGluR-5 shRNA Plasmid (r)

sc-270671-SHrGene SilencingPuromycin0
(0)

mGluR-5 shRNA (r) Lentiviral Particles

sc-270671-VrGene SilencingPuromycin0
(0)