Date published: 2026-8-15

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Mfn Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Mfn Antibodies for studying mitofusins, which play a crucial role in mitochondrial fusion and function. Mfn Antibodies are compatible with multiple research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Mitofusins, specifically Mfn1 and Mfn2, are essential for maintaining mitochondrial morphology and regulating energy metabolism within cells. Mfn1 and Mfn2 participate in various cellular processes, including apoptosis and cellular stress response. Research has shown that Mfn1 and Mfn2 have significant implications in neurodegenerative diseases and metabolic disorders. Understanding the role of mitofusins can provide valuable insights into potential therapeutic approaches for various pathological conditions. Scientists investigating mitochondrial dynamics frequently rely on Mfn1 and Mfn2 detection methods to advance their research. The high-quality monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to make meaningful contributions to understanding mitochondrial biology and disease mechanisms.

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Mfn Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Mfn1/Mitofusin 1 Antibody (D-10)

sc-166644mouse IgG2a κ10-74 (h)WB, IP, IF, ELISAm, r, h
113
(31)

Mfn2/Mitofusin 2 Antibody (F-5)

sc-515647mouse IgG1 κ461-528 (h)WB, IP, IF, ELISAm, r, h
53
(22)

Mfn2/Mitofusin 2 Antibody (XX-1)

sc-100560mouse IgG2a κ661-757 (h)WB, IP, IF, IHC(P), ELISAm, r, h
118
(13)

Mfn siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Mfn1/Mitofusin 1 siRNA (h)

sc-43927hGene SilencingN/A
7
(0)

Mfn1/Mitofusin 1 shRNA Plasmid (h)

sc-43927-SHhGene SilencingPuromycin
7
(0)

Mfn1/Mitofusin 1 shRNA (h) Lentiviral Particles

sc-43927-VhGene SilencingPuromycin
7
(0)

Mfn1/Mitofusin 1 siRNA (m)

sc-60082mGene SilencingN/A0
(0)

Mfn1/Mitofusin 1 shRNA Plasmid (m)

sc-60082-SHmGene SilencingPuromycin0
(0)

Mfn1/Mitofusin 1 shRNA (m) Lentiviral Particles

sc-60082-VmGene SilencingPuromycin0
(0)

Mfn1/Mitofusin 1 siRNA (r)

sc-270320rGene SilencingN/A
1
(0)

Mfn1/Mitofusin 1 shRNA Plasmid (r)

sc-270320-SHrGene SilencingPuromycin
1
(0)

Mfn1/Mitofusin 1 shRNA (r) Lentiviral Particles

sc-270320-VrGene SilencingPuromycin
1
(0)

Mfn2/Mitofusin 2 siRNA (h)

sc-43928hGene SilencingN/A
18
(0)

Mfn2/Mitofusin 2 shRNA Plasmid (h)

sc-43928-SHhGene SilencingPuromycin
18
(0)

Mfn2/Mitofusin 2 shRNA (h) Lentiviral Particles

sc-43928-VhGene SilencingPuromycin
18
(0)

Mfn2/Mitofusin 2 siRNA (m)

sc-60077mGene SilencingN/A
6
(0)

Mfn2/Mitofusin 2 shRNA Plasmid (m)

sc-60077-SHmGene SilencingPuromycin
6
(0)

Mfn2/Mitofusin 2 shRNA (m) Lentiviral Particles

sc-60077-VmGene SilencingPuromycin
6
(0)

Mfn2/Mitofusin 2 siRNA (r)

sc-156013rGene SilencingN/A
4
(0)

Mfn2/Mitofusin 2 shRNA Plasmid (r)

sc-156013-SHrGene SilencingPuromycin
4
(0)

Mfn2/Mitofusin 2 shRNA (r) Lentiviral Particles

sc-156013-VrGene SilencingPuromycin
4
(0)

Mfn CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Mfn1/Mitofusin 1 CRISPR/Cas9 KO Plasmid (h)

sc-400637Gene Knockouth0
(0)

Mfn1/Mitofusin 1 HDR Plasmid (h)

sc-400637-HDRHomology Directed Repairh0
(0)

Mfn1/Mitofusin 1 CRISPR/Cas9 KO Plasmid (m)

sc-426545Gene Knockoutm0
(0)

Mfn1/Mitofusin 1 HDR Plasmid (m)

sc-426545-HDRHomology Directed Repairm0
(0)

Mfn2/Mitofusin 2 CRISPR/Cas9 KO Plasmid (h)

sc-400536Gene Knockouth0
(0)

Mfn2/Mitofusin 2 HDR Plasmid (h)

sc-400536-HDRHomology Directed Repairh0
(0)

Mfn2/Mitofusin 2 CRISPR/Cas9 KO Plasmid (m)

sc-431291Gene Knockoutm0
(0)

Mfn2/Mitofusin 2 HDR Plasmid (m)

sc-431291-HDRHomology Directed Repairm0
(0)

Mfn CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Mfn1/Mitofusin 1 Double Nickase Plasmid (h)

sc-400637-NICGene Knockouth0
(0)

Mfn1/Mitofusin 1 Double Nickase Plasmid (h2)

sc-400637-NIC-2Gene Knockouth0
(0)

Mfn1/Mitofusin 1 Double Nickase Plasmid (m)

sc-426545-NICGene Knockoutm0
(0)

Mfn1/Mitofusin 1 Double Nickase Plasmid (m2)

sc-426545-NIC-2Gene Knockoutm0
(0)

Mfn2/Mitofusin 2 Double Nickase Plasmid (h)

sc-400536-NICGene Knockouth0
(0)

Mfn2/Mitofusin 2 Double Nickase Plasmid (h2)

sc-400536-NIC-2Gene Knockouth0
(0)

Mfn2/Mitofusin 2 Double Nickase Plasmid (m)

sc-431291-NICGene Knockoutm0
(0)

Mfn CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Mfn1/Mitofusin 1 CRISPR Activation Plasmid (h)

sc-400637-ACTGene Activationh0
(0)

Mfn1/Mitofusin 1 CRISPR Activation Plasmid (m)

sc-426545-ACTGene Activationm0
(0)

Mfn1/Mitofusin 1 CRISPR Activation Plasmid (m2)

sc-426545-ACT-2Gene Activationm0
(0)

Mfn1/Mitofusin 1 Lentiviral Activation Particles (m)

sc-426545-LACGene Activationm0
(0)

Mfn2/Mitofusin 2 CRISPR Activation Plasmid (h)

sc-400536-ACTGene Activationh0
(0)

Mfn2/Mitofusin 2 CRISPR Activation Plasmid (h2)

sc-400536-ACT-2Gene Activationh0
(0)

Mfn2/Mitofusin 2 Lentiviral Activation Particles (h)

sc-400536-LACGene Activationh0
(0)

Mfn2/Mitofusin 2 Lentiviral Activation Particles (h2)

sc-400536-LAC-2Gene Activationh0
(0)

Mfn2/Mitofusin 2 CRISPR Activation Plasmid (m)

sc-431291-ACTGene Activationm0
(0)

Mfn2/Mitofusin 2 CRISPR Activation Plasmid (m2)

sc-431291-ACT-2Gene Activationm0
(0)