METTL11B Activators represent a specific category of chemical compounds that have gained attention in the field of molecular biology and biochemistry due to their role in modulating the activity of the METTL11B gene. METTL11B, or Methyltransferase Like 11B, is a protein-coding gene found in humans, and it is part of the methyltransferase enzyme family. Methyltransferases are essential for the addition of methyl groups to various biomolecules, including DNA, RNA, and proteins, playing a crucial role in regulating gene expression, protein function, and cellular processes. METTL11B Activators are a group of molecules designed to enhance or stimulate the expression and function of the METTL11B gene, leading to increased activity of the associated protein.
The mechanism of action of METTL11B Activators typically involves their interaction with specific regulatory elements within the METTL11B gene's promoter region or enhancer sequences. This interaction can result in the upregulation of gene transcription and the subsequent synthesis of the METTL11B protein. The METTL11B protein is believed to be involved in the methylation of specific substrates, potentially impacting various cellular processes and molecular pathways. As researchers continue to explore the functions and downstream effects of METTL11B activation, the development and refinement of METTL11B Activators hold promise for advancing our understanding of epigenetic modifications and their implications in various scientific and molecular contexts, such as gene regulation and protein modification.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $180.00 $655.00 | 2 | |
As a universal methyl donor, S-Adenosylmethionine might upregulate METTL11B as part of a feedback mechanism to ensure adequate methylation capacity in response to increased demand. | ||||||
Mecobalamin | 13422-55-4 | sc-211781 | 10 mg | $300.00 | ||
As a form of vitamin B12 used in methylation pathways, methylcobalamin might influence the expression of methylation-related enzymes like METTL11B to support methylation processes. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
As a key molecule in one-carbon metabolism, folic acid is essential for the generation of S-Adenosylmethionine, and its supplementation might indirectly upregulate METTL11B to enhance methylation capacity. | ||||||
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $30.00 $40.00 $55.00 $160.00 $330.00 $580.00 | 2 | |
Betaine donates methyl groups in the methionine cycle, potentially increasing the demand for methylation enzymes like METTL11B as part of a broader response to maintain methylation homeostasis. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
As a precursor to NAD+, nicotinamide might influence sirtuin activity and subsequently affect the expression of genes like METTL11B involved in methylation and cellular stress responses. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
This polyphenol affects various signaling pathways and might upregulate METTL11B as part of its broad effects on gene expression, particularly in pathways related to aging and stress resistance. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Known for its effect on numerous cellular pathways, curcumin might induce METTL11B expression as part of its anti-inflammatory and antioxidative properties, influencing cellular methylation patterns. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
As a regulator of gene expression through nuclear receptors, retinoic acid might affect the expression of enzymes like METTL11B involved in post-translational modifications and cell differentiation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Found in green tea, this compound could modulate gene expression and methylation status, potentially leading to upregulation of METTL11B as part of its cancer-preventative effects. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
As an isothiocyanate from cruciferous vegetables, sulforaphane might induce METTL11B expression through its effects on antioxidant response elements and detoxification enzymes. | ||||||