MBLAC1 Activators
MBLAC1 Activators are a collection of chemical compounds that are believed to influence the function of MBLAC1, a protein critical in calcium-dependent cellular processes. These activators function by altering the intracellular calcium levels closely linked to the activities that MBLAC1 is known to be involved in. NMDA, a specific agonist of NMDA receptors, and Carbachol, a cholinergic agonist, for example, increase intracellular calcium levels, potentially leading to increased functional activity of MBLAC1. On the other hand, BAPTA-AM, a cell-permeable calcium chelator, and SKF-96365, an inhibitor of receptor-mediated calcium entry, can modulate intracellular calcium levels, potentially affecting MBLAC1 activity.
Other compounds such as DHPG, a group I mGluR agonist, and Ryanodine, a ryanodine receptor agonist, trigger calcium release from intracellular stores, potentially leading to enhanced activity of the calcium-dependent MBLAC1. Bay K 8644, an L-type calcium channel agonist, and Thapsigargin, a SERCA pump inhibitor, increase intracellular calcium levels, potentially enhancing MBLAC1 activity. Meanwhile, A-23187, an ionophore that transports calcium across cell membranes, and Ionomycin, a calcium ionophore, increase intracellular calcium levels, potentially leading to enhanced MBLAC1 activity. Therefore, these activators, although varied in their biochemical targets and actions, can all logically activate MBLAC1 through their impacts on intracellular calcium levels.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-Methyl-D-Aspartic acid (NMDA) | 6384-92-5 | sc-200458 sc-200458A | 50 mg 250 mg | $107.00 $362.00 | 2 | |
NMDA is a specific agonist of NMDA receptors, which are known to play a role in neuronal plasticity and excitotoxicity. Activation of these receptors can induce calcium ion influx, potentially leading to increased MBLAC1 activity due to its calcium-dependent metalloprotease nature. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
BAPTA-AM is a cell-permeable calcium chelator. It can modulate intracellular calcium levels, and since MBLAC1 is a calcium-dependent protease, alterations in calcium levels can affect MBLAC1 activity. | ||||||
Carbachol | 51-83-2 | sc-202092 sc-202092A sc-202092C sc-202092D sc-202092B sc-202092E | 1 g 10 g 25 g 50 g 100 g 250 g | $120.00 $275.00 $380.00 $670.00 $1400.00 $3000.00 | 12 | |
Carbachol is a cholinergic agonist which increases intracellular calcium. Increased calcium can lead to enhanced MBLAC1 activity, given its calcium-dependent nature. | ||||||
(S)-3,5-DHPG | 162870-29-3 | sc-204256 sc-204256A | 5 mg 10 mg | $206.00 $346.00 | 2 | |
DHPG is a group I mGluR agonist that triggers calcium release from intracellular stores, potentially leading to enhanced activity of the calcium-dependent MBLAC1. | ||||||
(±)-Bay K 8644 | 71145-03-4 | sc-203324 sc-203324A sc-203324B | 1 mg 5 mg 50 mg | $82.00 $192.00 $801.00 | ||
Bay K 8644 is an L-type calcium channel agonist. It increases intracellular calcium, potentially leading to enhanced MBLAC1 activity. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin is a SERCA pump inhibitor that increases intracellular calcium levels. This can enhance the activity of the calcium-dependent MBLAC1. | ||||||
Ryanodine | 15662-33-6 | sc-201523 sc-201523A | 1 mg 5 mg | $219.00 $765.00 | 19 | |
Ryanodine is a ryanodine receptor agonist which releases calcium from intracellular stores. This could lead to enhanced MBLAC1 activity. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A-23187 is an ionophore that transports calcium across cell membranes, leading to increased intracellular calcium levels, potentially enhancing MBLAC1 activity. | ||||||
Cyclopiazonic Acid | 18172-33-3 | sc-201510 sc-201510A | 10 mg 50 mg | $173.00 $612.00 | 3 | |
Cyclopiazonic Acid is a specific inhibitor of the SERCA pump, which can increase intracellular calcium levels, potentially enhancing MBLAC1 activity. | ||||||
SK&F 96365 | 130495-35-1 | sc-201475 sc-201475B sc-201475A sc-201475C | 5 mg 10 mg 25 mg 50 mg | $101.00 $155.00 $389.00 $643.00 | 2 | |
SKF-96365 is an inhibitor of receptor-mediated calcium entry, potentially modulating MBLAC1 activity through changes in calcium levels. | ||||||