MAN1C1 Activators
MAN1C1 activators belong to a distinctive chemical class known for their ability to modulate the activity of MAN1C1, an enzyme encoded by the MAN1C1 gene. MAN1C1, or Mannosidase alpha class 1C member 1, is a glycosyl hydrolase enzyme that plays a crucial role in glycoprotein processing within the cell. Activators of MAN1C1 are molecules capable of influencing the function of this enzyme, either by enhancing its catalytic activity or by regulating its interaction with other cellular components. These activators are essential for the fine-tuning of glycoprotein metabolism, which is vital for maintaining cellular homeostasis and proper functioning of various biological processes.
Structurally, MAN1C1 activators may exhibit diverse chemical architectures, reflecting the complexity required to interact with the enzyme target effectively. These molecules may possess specific binding motifs or functional groups that facilitate their engagement with MAN1C1, enabling them to modulate its activity in a precise manner. Understanding the structural features and biochemical properties of MAN1C1 activators is critical for unraveling the regulatory mechanisms governing glycoprotein processing and cellular physiology. Further exploration of the pharmacological characteristics and biological roles of MAN1C1 activators holds the promise of advancing our understanding of glycoprotein metabolism and may offer insights into novel strategies for manipulating cellular functions in various biological contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can regulate gene expression through its receptors, potentially enhancing MAN1C1 expression as part of cellular differentiation processes. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
By inhibiting N-linked glycosylation, tunicamycin may induce a cellular stress response that upregulates MAN1C1 as a compensatory mechanism. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which can lead to the activation of various transcription factors potentially affecting MAN1C1 expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methyltransferase inhibitor, 5-azacytidine can alter gene expression patterns, potentially upregulating MAN1C1 by changing the methylation status of its promoter. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
This histone deacetylase inhibitor can change chromatin structure, potentially increasing the accessibility of the MAN1C1 gene to transcription factors. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate, another histone deacetylase inhibitor, may enhance MAN1C1 expression through epigenetic modifications leading to a more open chromatin state around the gene. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
As a major component of green tea, EGCG can influence numerous signaling pathways and might upregulate MAN1C1 expression as part of its broad biological effects. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
By inducing ER stress, thapsigargin might enhance the expression of genes like MAN1C1 involved in the unfolded protein response (UPR) pathway. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol influences various signaling pathways, including those related to stress response and longevity, which might include upregulation of MAN1C1. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride can activate Wnt signaling pathway, which may have downstream effects on gene expression, potentially including MAN1C1. | ||||||