LYPLA1 Activators
LYPLA1 activators belong to a class of chemical compounds designed to modulate the activity of the enzyme lysophospholipase 1, also known as LYPLA1. This enzyme plays a critical role in lipid metabolism, particularly in the hydrolysis of lysophospholipids, which are key intermediates in the synthesis and degradation of complex cellular lipids such as phospholipids and glycerophospholipids. LYPLA1 is primarily localized to the endoplasmic reticulum and is involved in maintaining cellular lipid homeostasis by regulating the levels of lysophospholipids.
LYPLA1 activators are specifically engineered to interact with LYPLA1, potentially influencing its enzymatic activity. By targeting LYPLA1, these compounds may enhance or inhibit its ability to catalyze the hydrolysis of lysophospholipids, consequently impacting cellular lipid composition and metabolism. The study of LYPLA1 activators offers insights into the complex mechanisms of lipid metabolism and the regulatory processes that govern cellular lipid homeostasis. Further research is necessary to elucidate the precise mechanisms of action and the potential biological consequences associated with LYPLA1 activation, offering valuable insights into cellular physiology and lipid-related pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Palmitic Acid | 57-10-3 | sc-203175 sc-203175A | 25 g 100 g | $112.00 $280.00 | 2 | |
As a common fatty acid involved in protein S-acylation, palmitic acid might influence the expression of enzymes like LYPLA1 that modulate fatty acid modifications. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin regulates many aspects of lipid metabolism and might influence the expression of enzymes like LYPLA1. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
Metformin affects cellular energy homeostasis and lipid metabolism, potentially influencing LYPLA1 expression. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
As a PPARγ agonist, rosiglitazone modulates lipid metabolism, potentially affecting enzymes like LYPLA1. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
Fenofibrate, a PPARα agonist, affects lipid metabolism, which might influence the expression of LYPLA1. | ||||||
Lovastatin | 75330-75-5 | sc-200850 sc-200850A sc-200850B | 5 mg 25 mg 100 mg | $28.00 $88.00 $332.00 | 12 | |
Lovastatin inhibits cholesterol synthesis. By altering lipid homeostasis, it might influence LYPLA1 expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can influence cellular differentiation and lipid metabolism, potentially affecting LYPLA1 expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone, a glucocorticoid, can influence lipid metabolism and might modulate the expression of LYPLA1. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $36.00 $102.00 $569.00 $1173.00 | 10 | |
Oleic acid, a monounsaturated fatty acid, might influence lipid metabolism pathways and thus the expression of enzymes like LYPLA1. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has been shown to influence lipid metabolism, which might impact the expression of LYPLA1. | ||||||