Ly-49D Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
PP2 is an Src family kinase inhibitor which can functionally inhibit Ly-49D by blocking the Src family kinases that are upstream of the activation pathway, leading to the inhibition of Ly-49D signaling involved in natural killer (NK) cell activation. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
Dasatinib is a broad-spectrum tyrosine kinase inhibitor which inhibits multiple kinases including those involved in the signal transduction pathway of Ly-49D, thus functionally inhibiting the activation signal mediated by Ly-49D on NK cells. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Ly294002 is a phosphoinositide 3-kinase (PI3K) inhibitor which can inhibit downstream signaling pathways of Ly-49D by preventing PI3K-dependent activation steps, thereby functionally inhibiting Ly-49D signal transduction in NK cells. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD 98059 is a MEK inhibitor which can functionally inhibit the Ly-49D protein by blocking the MAPK/ERK pathway, a downstream pathway of Ly-49D signaling, leading to inhibition of NK cell functions mediated by Ly-49D. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is a selective inhibitor of both MEK1 and MEK2 which can functionally inhibit Ly-49D signaling by impeding the MAPK/ERK pathway, subsequently inhibiting Ly-49D-mediated NK cell activation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of c-Jun N-terminal kinase (JNK), which can functionally inhibit Ly-49D by blocking downstream JNK signaling pathways, leading to inhibition of NK cell functions that are mediated by Ly-49D activation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a p38 MAP kinase inhibitor which can functionally inhibit Ly-49D by blocking p38 MAPK signaling pathways that are involved in Ly-49D-mediated NK cell activation and function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a PI3K inhibitor that can functionally inhibit Ly-49D by preventing PI3K-dependent phosphorylation events, which are essential for signal transduction processes involving Ly-49D in NK cells. | ||||||
AG-490 | 133550-30-8 | sc-202046C sc-202046A sc-202046B sc-202046 | 5 mg 50 mg 25 mg 10 mg | $84.00 $329.00 $223.00 $87.00 | 35 | |
AG490 is a JAK2 inhibitor which can functionally inhibit Ly-49D by impeding the JAK/STAT signaling pathway, thereby inhibiting the signal transduction that is mediated by Ly-49D on NK cells. | ||||||
Gö 6976 | 136194-77-9 | sc-221684 | 500 µg | $227.00 | 8 | |
Gö6976 is a protein kinase C (PKC) inhibitor which can functionally inhibit Ly-49D signaling by blocking PKC-dependent pathways that are involved in the activation of NK cells by Ly-49D. | ||||||