LRRC72 Inhibitors
LRRC72 inhibitors constitute a chemical class targeting LRRC72 through modulation of the TGF-β signaling pathway. TGF-β (Transforming Growth Factor-beta) is a key signaling cascade that regulates various cellular processes, including cell growth, differentiation, and immune responses. LRRC72, being associated with this pathway, can be influenced by specific inhibitors targeting crucial components of TGF-β signaling.
Several compounds in the LRRC72 inhibitors class, such as A83-01, SB431542, and Galunisertib, act by inhibiting TGF-β type I receptor, potentially disrupting LRRC72 activation. LY2157299, LDN-214117, and RepSox also impact LRRC72 through inhibition of TGF-β receptor type I. Additionally, compounds like SIS3 and LY364947 target downstream effectors like Smad3, influencing LRRC72 signaling. SD-208, EW-7197, ITD-1, and LY2109761 further contribute to LRRC72 inhibition by targeting TGF-β receptor type I. These inhibitors collectively offer a comprehensive approach to studying LRRC72 by specifically intervening in the TGF-β signaling pathway. Understanding LRRC72 inhibitors can provide valuable insights into the regulatory mechanisms of this protein and its potential implications in cellular processes and diseases.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
A 83-01 | 909910-43-6 | sc-203791 sc-203791A | 10 mg 50 mg | $198.00 $650.00 | 16 | |
A83-01 is an inhibitor of TGF-β type I receptor, potentially affecting LRRC72 through the TGF-β signaling pathway. Its action disrupts downstream events linked to LRRC72 activation. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
SB431542 inhibits the TGF-β type I receptor, impacting LRRC72 signaling. Its interference with this pathway can lead to the inhibition of LRRC72 functionality. | ||||||
LY2157299 | 700874-72-2 | sc-391123 sc-391123A | 5 mg 10 mg | $209.00 $352.00 | 3 | |
LY2157299 inhibits TGF-β receptor type I, potentially affecting LRRC72 through the TGF-β signaling pathway. Its action disrupts downstream events linked to LRRC72 activation. | ||||||
LY2109761 | 700874-71-1 | sc-396262 sc-396262A | 1 mg 5 mg | $87.00 $270.00 | 9 | |
LY2157299 is a TGF-β receptor type I inhibitor, influencing LRRC72 through the TGF-β signaling pathway. Its action disrupts downstream events linked to LRRC72 activation. | ||||||
Caspase-1 Inhibitor II | 178603-78-6 | sc-300323 sc-300323A | 5 mg 25 mg | $255.00 $1224.00 | 7 | |
SIS3 inhibits Smad3, a downstream effector in the TGF-β signaling pathway. By disrupting Smad3, SIS3 can potentially impact LRRC72 signaling, leading to its inhibition. | ||||||
LDN-214117 | 1627503-67-6 | sc-507451 | 5 mg | $165.00 | ||
LDN-214117 inhibits ALK4, a TGF-β type I receptor, potentially influencing LRRC72 through the TGF-β signaling pathway. Its action disrupts downstream events linked to LRRC72 activation. | ||||||
ALK5 Inhibitor II | 446859-33-2 | sc-221234 sc-221234A sc-221234B sc-221234C sc-221234D sc-221234E sc-221234F | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 g | $75.00 $150.00 $215.00 $650.00 $1224.00 $4296.00 $7818.00 | 8 | |
RepSox inhibits TGF-β type I receptor, potentially affecting LRRC72 through the TGF-β signaling pathway. Its action disrupts downstream events linked to LRRC72 activation. | ||||||
LY 364947 | 396129-53-6 | sc-203122 sc-203122A | 5 mg 10 mg | $105.00 $153.00 | 4 | |
LY364947 is a TGF-β receptor type I inhibitor, influencing LRRC72 through the TGF-β signaling pathway. Its action disrupts downstream events linked to LRRC72 activation. | ||||||
TGF-β RI Kinase Inhibitor V | 627536-09-8 | sc-203294 | 2 mg | $86.00 | 3 | |
SD-208 inhibits TGF-β receptor type I, potentially affecting LRRC72 through the TGF-β signaling pathway. Its action disrupts downstream events linked to LRRC72 activation. | ||||||
EW-7197 | 1352608-82-2 | sc-507465 | 5 mg | $345.00 | ||
EW-7197 is a TGF-β receptor type I inhibitor, influencing LRRC72 through the TGF-β signaling pathway. Its action disrupts downstream events linked to LRRC72 activation. | ||||||