LRRC64 Inhibitors
LRRC64 inhibitors belong to a diverse class of compounds that modulate cellular signaling pathways crucial for LRRC64-related functions. These inhibitors act through distinct mechanisms, influencing LRRC64-associated cellular processes, including gene expression, proliferation, and differentiation.
Forskolin, an activator of adenylate cyclase, stimulates cAMP/PKA signaling, impacting LRRC64-related pathways. Ionomycin induces calcium influx, potentially affecting calcium-dependent signaling cascades associated with LRRC64. PMA activates PKC, modulating downstream pathways and influencing LRRC64-related cellular functions. IBMX, as a phosphodiesterase inhibitor, elevates cAMP levels, stimulating LRRC64 pathways.
Thapsigargin induces ER stress, potentially impacting LRRC64-related cellular processes. Bay K 8644 enhances calcium influx, influencing calcium-dependent signaling cascades. Dibutyryl-cAMP, a cAMP analog, stimulates cAMP/PKA signaling, affecting LRRC64-related pathways. A23187, a calcium ionophore, modulates calcium-dependent signaling pathways associated with LRRC64.
Cholera toxin and CGS 21680, by activating adenylate cyclase and A2A receptors, respectively, modulate signaling cascades influencing LRRC64-related functions. FPL 64176, a positive allosteric modulator of L-type calcium channels, enhances calcium influx, potentially impacting LRRC64-associated pathways. These LRRC64 inhibitors collectively
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin is a calcium ionophore that induces calcium influx into cells. Increased intracellular calcium levels can activate various signaling pathways, potentially influencing LRRC64-related cellular processes. Ionomycin may modulate LRRC64 pathways by altering calcium-dependent signaling cascades, leading to changes in gene expression or cellular functions. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC), a family of kinases involved in cell signaling. PKC activation can impact downstream pathways, potentially influencing LRRC64-related cellular processes. PMA may stimulate LRRC64 pathways by modulating PKC-dependent signaling, leading to alterations in gene expression or cellular functions associated with LRRC64. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX inhibits phosphodiesterases, leading to increased cAMP levels. Elevated cAMP can activate PKA, influencing downstream cellular processes. IBMX may stimulate LRRC64-related pathways by modulating cAMP/PKA signaling, impacting cell proliferation, differentiation, or gene expression. | ||||||
8-Bromo-cGMP | 51116-01-9 | sc-200316 sc-200316A | 10 mg 50 mg | $104.00 $354.00 | 7 | |
8-Bromo-cGMP is a cell-permeable analog of cyclic guanosine monophosphate (cGMP). It can activate protein kinase G (PKG) and influence downstream signaling pathways. 8-Bromo-cGMP may stimulate LRRC64-related pathways by modulating cGMP/PKG signaling, leading to changes in gene expression or cellular functions. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin induces endoplasmic reticulum (ER) stress by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) pump. ER stress can activate various signaling pathways, potentially influencing LRRC64-related cellular processes. Thapsigargin may modulate LRRC64 pathways by inducing ER stress, leading to alterations in gene expression or cellular functions. | ||||||
(±)-Bay K 8644 | 71145-03-4 | sc-203324 sc-203324A sc-203324B | 1 mg 5 mg 50 mg | $84.00 $196.00 $817.00 | ||
Bay K 8644 is a calcium channel activator, enhancing calcium influx into cells. Increased intracellular calcium levels can influence various signaling pathways, potentially impacting LRRC64-related cellular processes. Bay K 8644 may stimulate LRRC64 pathways by modulating calcium-dependent signaling cascades, leading to changes in gene expression or cellular functions. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
Dibutyryl-cAMP is a cell-permeable analog of cAMP. It can activate PKA, influencing downstream cellular processes. Dibutyryl-cAMP may stimulate LRRC64-related pathways by modulating cAMP/PKA signaling, impacting cell proliferation, differentiation, or gene expression. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187 is a calcium ionophore that facilitates calcium influx into cells. Increased intracellular calcium levels can activate various signaling pathways, potentially influencing LRRC64-related cellular processes. A23187 may modulate LRRC64 pathways by altering calcium-dependent signaling cascades, leading to changes in gene expression or cellular functions. | ||||||