LRRC38 activators belong to a specialized class of chemical compounds that have gained recognition within the field of molecular biology and genetics. These compounds are engineered to modulate the activity of LRRC38, a protein-coding gene that plays a role in various cellular processes. LRRC38, which stands for Leucine-Rich Repeat-Containing Protein 38, is characterized by the presence of leucine-rich repeat (LRR) domains, suggesting its involvement in protein-protein interactions and cellular signaling. LRRC38 activators function by targeting specific regulatory elements within the LRRC38 gene, often located in promoter or enhancer regions, with the primary aim of enhancing its transcription and subsequent translation into functional protein products.
The precise mechanisms through which LRRC38 activators exert their effects may vary, but their core purpose is to act as molecular switches, amplifying the activity of LRRC38. Researchers are continually exploring the potential applications and implications of LRRC38 activation, with the goal of deepening our understanding of how this gene contributes to cellular processes, particularly in the context of protein-protein interactions and cellular signaling pathways. This class of compounds holds promise for advancing our knowledge of gene regulation, particularly within the domain of leucine-rich repeat-containing proteins, offering insights into the intricate mechanisms that govern cellular communication and the role of LRRC38 in various biological contexts. LRRC38 activators represent a valuable tool in the ongoing exploration of molecular biology, providing opportunities to uncover the complex roles that LRRC38 plays in cellular processes and its significance in protein-protein interactions and cellular signaling.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin directly stimulates adenylyl cyclase, increasing cyclic AMP (cAMP) levels, which may lead to the activation of cAMP-dependent protein kinase (PKA) and modulation of protein phosphorylation, potentially affecting LRR-containing protein function. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
As a diacylglycerol analog, PMA activates protein kinase C (PKC), which may alter phosphorylation states of proteins, including those with LRR domains, thereby influencing their activity. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
This cAMP analog is membrane-permeable and activates PKA, potentially influencing phosphorylation and activity of LRR-containing proteins through downstream signaling cascades. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is known to modulate various signaling pathways and could indirectly influence the activity or expression of LRR-containing proteins. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
As a tyrosine kinase inhibitor, Genistein may affect phosphorylation cascades and potentially alter the function of proteins with LRR domains by modulating the signaling pathways they are involved in. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
A polyphenol that can modulate multiple cellular pathways, potentially influencing the activity of LRR-containing proteins indirectly. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
This histone deacetylase inhibitor can alter gene expression profiles, potentially affecting the expression of LRR-containing proteins. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that can impact various signaling pathways, potentially influencing the function of proteins that contain LRR domains. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
This p38 MAPK inhibitor could alter signaling pathways and indirectly affect the activity of LRR-containing proteins. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, and could modulate signaling pathways involving LRR-containing proteins. | ||||||