LRFN3 Inhibitors
The chemical class termed as LRFN3 inhibitors comprises compounds that don't directly target LRFN3, but rather impact signaling pathways and interactions that LRFN3 might be involved in. The precise nature and scope of LRFN3's activities in cells remain a subject of ongoing research, but these compounds offer routes for influencing its behavior. PKC, MAPK/ERK, PLC, and PI3K/Akt pathways are central to numerous cellular processes, from proliferation to differentiation. As such, chemicals like PD98059, U73122, and Wortmannin, which modulate these pathways, can have extensive downstream effects, including the modulation of LRFN3's activity.
Moreover, LRFN3's activity might be influenced by calcium signaling, as suggested by the impact of BAPTA-AM and KN-93, which affect intracellular calcium levels and calcium-dependent kinases, respectively. Interactions with actin cytoskeleton dynamics, modulated by Y-27632 and ML7, further underline the intricate network of cellular processes that can influence and be influenced by LRFN3. This breadth o interactions underscores the challenge and importance of defining specific inhibitors for such proteins. It's a testament to the interconnected nature of cellular signaling and the imperative for rigorous validation when identifying and characterizing protein modulators.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor. If LRFN3 operates in the p38 MAPK pathway, its function can be influenced by SB203580. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a MEK inhibitor. If LRFN3's activity is linked with the MAPK/ERK pathway, PD98059 can indirectly influence its function. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
KN-93 is a CaMKII inhibitor. If LRFN3 interacts with or is regulated by CaMKII, its function can be influenced by KN-93. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a PI3K inhibitor. If LRFN3 operates within the PI3K/Akt pathway, its function can be modulated by Wortmannin. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is another PI3K inhibitor. If LRFN3's function is influenced by the PI3K/Akt pathway, LY294002 can adjust its activity. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
PP2 is a Src family kinase inhibitor. If LRFN3 has interactions regulated by Src kinases, its function can be modulated by PP2. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632 is a ROCK inhibitor. If LRFN3's activity is associated with Rho/ROCK pathways, its function can be impacted by Y-27632. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
BAPTA-AM is a calcium chelator. If LRFN3's function is calcium-dependent, its activity can be influenced by altering intracellular calcium levels using BAPTA-AM. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
Go 6983 is a broad-spectrum PKC inhibitor. If LRFN3's function is intertwined with PKC signaling, its activity can be influenced by Go 6983. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $89.00 $262.00 | 13 | |
ML7 is a myosin light chain kinase inhibitor. If LRFN3 interacts with actin dynamics influenced by this kinase, ML7 can modulate its activity. | ||||||