Date published: 2026-2-22

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LOC85449 Activators

KIAA1755 is a protein that, similar to the LOC nomenclature, has been identified through systematic sequencing of large genomic regions but has not been thoroughly characterized in terms of function. The "KIAA" prefix denotes that the protein was first identified in a large-scale cDNA sequencing project conducted by the Kazusa DNA Research Institute in Japan. The number "1755" serves as a unique identifier for this specific protein within the KIAA project database.The KIAA1755 protein is encoded by a gene that is predicted based on the sequence of cDNA clones. The gene's mRNA expression patterns, as well as the predicted amino acid sequence of the protein, may provide preliminary clues about its function. Often, KIAA proteins are of interest because they may represent novel proteins with potential roles in cellular biology that have not been previously described.

The study of KIAA1755 would include examining its sequence for recognizable motifs, domains, or signatures that could suggest a biological function. For example, a DNA binding domain might imply a role in transcriptional regulation, while a kinase domain might suggest involvement in signal transduction pathways.Bioinformatics tools can be used to predict subcellular localization, post-translational modifications, and potential interaction partners for KIAA1755. Experimental approaches, such as gene knockdown or overexpression studies, protein interaction assays, and localization studies, are essential to confirm these predictions and determine the physiological role of KIAA1755.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

SERCA pump inhibitor, leads to increased cytosolic calcium levels, potentially affecting EFCAB14/KIAA1755 through calcium-related signaling pathways.

A23187

52665-69-7sc-3591
sc-3591B
sc-3591A
sc-3591C
1 mg
5 mg
10 mg
25 mg
$55.00
$131.00
$203.00
$317.00
23
(1)

Ionophore that increases intracellular calcium levels, potentially affecting EFCAB14/KIAA1755 activity by altering calcium-dependent signaling pathways.

2-APB

524-95-8sc-201487
sc-201487A
20 mg
100 mg
$28.00
$53.00
37
(1)

Modulates intracellular calcium release, potentially influencing EFCAB14/KIAA1755 activity through calcium signaling.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$78.00
$270.00
80
(4)

Increases intracellular calcium levels, potentially influencing EFCAB14/KIAA1755 activity through calcium-dependent signaling.

BAPTA/AM

126150-97-8sc-202488
sc-202488A
25 mg
100 mg
$138.00
$458.00
61
(2)

Intracellular calcium chelator, could indirectly affect EFCAB14/KIAA1755 activity by modulating calcium signaling.

EGTA

67-42-5sc-3593
sc-3593A
sc-3593B
sc-3593C
sc-3593D
1 g
10 g
100 g
250 g
1 kg
$21.00
$65.00
$120.00
$251.00
$815.00
23
(1)

Calcium chelator, used to study the role of extracellular calcium, could indirectly influence EFCAB14/KIAA1755.

Nimodipine

66085-59-4sc-201464
sc-201464A
100 mg
1 g
$61.00
$307.00
2
(1)

Calcium channel blocker, primarily L-type, potentially influencing EFCAB14/KIAA1755 activity by altering calcium influx.

Verapamil

52-53-9sc-507373
1 g
$374.00
(0)

Another calcium channel blocker, affects calcium influx, potentially influencing EFCAB14/KIAA1755 activity.

Ryanodine

15662-33-6sc-201523
sc-201523A
1 mg
5 mg
$223.00
$799.00
19
(2)

Modulates calcium release from sarcoplasmic/endoplasmic reticulum, could affect EFCAB14/KIAA1755 activity.

SK&F 96365

130495-35-1sc-201475
sc-201475B
sc-201475A
sc-201475C
5 mg
10 mg
25 mg
50 mg
$103.00
$158.00
$397.00
$656.00
2
(1)

Inhibitor of store-operated calcium entry, potentially influencing EFCAB14/KIAA1755 activity.