Date published: 2025-10-30

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LOC729690 Activators

Epigallocatechin Gallate, an antioxidant, can affect the NF-kB pathway, which plays a role in controlling the expression and activity of numerous proteins. SB203580 and LY294002, both kinase inhibitors, can shift the balance of cellular signaling, causing compensatory mechanisms that may affect protein function. Curcumin and Resveratrol have multiple targets within cells, including kinases and transcription factors, and SIRT1, respectively, which can lead to changes in protein activity.

Compounds like Genistein and Quercetin act as kinase inhibitors and have the capacity to modulate signaling pathways that are crucial for protein activation. Spermidine promotes autophagy, a process that can regulate protein levels and activity within the cell. Sodium Salicylate acts as an inhibitor of the NF-kB pathway, which can influence the inflammatory response and potentially alter protein function. PD98059 targets the MEK enzyme within the MAPK/ERK pathway, which is a key regulator of protein activity in response to various stimuli. Capsaicin can modify calcium signaling and affect the activity of proteins associated with TRPV channels. Dicoumarol's ability to alter cellular redox states can have implications for the function of redox-sensitive proteins.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

A catechin with antioxidant properties that can modulate signaling pathways like NF-kB, which can alter the activity of various proteins.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

A p38 MAPK inhibitor that can lead to the activation of alternate signaling pathways, impacting the activity of downstream proteins.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

A PI3K inhibitor which can cause compensatory activation in other signaling pathways, potentially influencing protein activity.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

A compound that can modulate the activity of various kinases and transcription factors, which can affect protein activity.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

A stilbenoid that can activate SIRT1, influencing cellular stress response pathways and potentially protein activity.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

An isoflavone that acts as a tyrosine kinase inhibitor, which can alter cellular signaling cascades and protein activity.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

A flavonoid that can inhibit PI3K and other kinases, thereby influencing signaling pathways and protein activity.

Spermidine

124-20-9sc-215900
sc-215900B
sc-215900A
1 g
25 g
5 g
$56.00
$595.00
$173.00
(2)

A polyamine that can induce autophagy, which in turn can affect the activity and turnover of various cellular proteins.

Sodium Salicylate

54-21-7sc-3520
sc-3520A
sc-3520B
sc-3520C
1 g
25 g
500 g
1 kg
$10.00
$25.00
$80.00
$136.00
8
(1)

An NF-kB inhibitor that can modulate inflammatory signaling pathways, potentially affecting protein activity.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

A specific MEK inhibitor which can modulate MAPK/ERK pathway activity, influencing downstream protein activity.