LOC728285 Inhibitors
LOC728285 inhibitors Rapamycin and LY294002 target key signaling pathways, such as mTOR and PI3K/AKT respectively, which are central to regulating cell growth, survival, and metabolism. Trichostatin A and 5-Fluorouracil intervene in gene expression and DNA synthesis processes, which could affect LOC728285 either at the transcriptional level or through dependency on DNA replication mechanisms for its function. Inhibitors like Roscovitine and U0126 can alter the cell cycle, potentially affecting the function of LOC728285 if it is cell cycle-regulated. Similarly, nocodazole's impact on microtubule dynamics could impact cellular division and trafficking processes, which in turn could alter the behavior or presence of LOC728285 in the cell.
MG132's inhibition of the proteasome system can influence the turnover of a wide range of proteins, including potentially LOC728285, by preventing its degradation. KN-93 and PD98059's targeting of CaMKII and MEK, respectively, affects calcium-dependent processes and the ERK signaling pathway which are pivotal in many cellular responses. Lastly, chemicals like SB431542 and Brefeldin A affect cells by inhibiting TGF-β receptor signaling and disrupting protein transport, which could have repercussions on the function or localization of LOC728285.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR, which can affect protein synthesis and cell growth, potentially influencing LOC728285 if it is involved in these processes. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Inhibits histone deacetylase (HDAC), which can alter gene expression, potentially affecting LOC728285 expression. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Disrupts microtubule polymerization, which can affect cell division, potentially impacting LOC728285 if it is associated with the cell cycle. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
Inhibits cyclin-dependent kinases (CDKs), which can alter cell cycle progression, potentially affecting LOC728285 if it is cell cycle-regulated. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
Inhibits thymidylate synthase, which can disrupt DNA synthesis, potentially impacting LOC728285 if it is involved in DNA replication or repair. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Inhibits the proteasome, which can affect protein degradation, potentially influencing LOC728285 stability. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, which can affect the AKT signaling pathway, potentially influencing processes regulated by LOC728285. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
Inhibits calmodulin-dependent kinase II (CaMKII), which can affect calcium signaling, potentially impacting LOC728285 if it is calcium-dependent. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK, which can affect the ERK signaling pathway, potentially influencing LOC728285 activity. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
Inhibits the TGF-β receptor, which can affect cellular differentiation and proliferation, potentially influencing LOC728285 if involved in these processes. | ||||||