LOC654106 Inhibitors
Wortmannin and LY294002 are phosphoinositide 3-kinase (PI3K) inhibitors that can alter the PI3K/AKT pathway, a critical regulator of cell survival and proliferation. Similarly, Rapamycin, by inhibiting mammalian target of rapamycin (mTOR), can exert influence over the processes that control protein synthesis and cellular metabolism, thereby impacting the functional context in which LOC654106 operates.
The MAPK pathway, another crucial signaling cascade involved in cell proliferation, differentiation, and survival, is targeted by PD98059, U0126, SB203580, and SP600125. These inhibitors, by modulating the activity of MEK and other kinases within the pathway, can affect the transcriptional regulation and protein interaction networks pertinent to LOC654106. Further downstream, MEK5 inhibition by BIX 02189 and the consequent effects on ERK5 signaling can also modulate the functional dynamics of LOC654106. Moreover, XMD8-92's inhibition of BMX/TEC kinases and SL327's inhibition of MEK1/2, along with Y-27632's inhibition of ROCK, offer additional mechanisms by which the signaling milieu of LOC654106 can be altered. The ROCK inhibitor, in particular, can impact cytoskeletal organization and cellular contractility, processes in which LOC654106 may play a role.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits PI3K, a kinase involved in signaling pathways that can regulate proteins like LOC654106. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor, which can alter downstream processes affecting LOC654106 activity. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $102.00 $138.00 | 14 | |
Targets the AKT signaling pathway, which can modulate the function of proteins including LOC654106. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR, a kinase that, when suppressed, can affect LOC654106's role in cell growth signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK, which is part of the MAPK pathway; altering this pathway can influence LOC654106. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Another MEK inhibitor, which can alter the MAPK/ERK pathway and thus LOC654106's associated processes. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibits p38 MAP kinase, potentially affecting LOC654106 by altering stress response signaling. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, which can modulate transcription factors that regulate LOC654106. | ||||||
BIX 02189 | 1094614-85-3 | sc-364436 sc-364436A | 5 mg 10 mg | $220.00 $378.00 | 5 | |
Inhibits MEK5, impacting the ERK5 pathway and potentially the function of LOC654106. | ||||||
XMD 8-92 (free base) | 1234480-50-2 | sc-364068 sc-364068A sc-364068B sc-364068C | 5 mg 10 mg 100 mg 1 g | $235.00 $340.00 $1700.00 $10330.00 | 10 | |
Targets BMX/TEC kinases, possibly affecting signaling pathways involving LOC654106. | ||||||