LOC645023 Activators
Compounds such as Forskolin and IBMX increase the levels of cAMP within the cell, leading to the activation of PKA which then has the potential to phosphorylate and modulate proteins including LOC645023. Other chemicals, like PMA, directly stimulate PKC, which is part of a signaling cascade that can lead to the activation of LOC645023. Changes in intracellular calcium levels brought about by Ionomycin can affect calcium-dependent proteins and signaling pathways, potentially resulting in the activation of LOC645023. Modifiers of gene expression, such as Sodium Butyrate, can induce changes in the transcriptional landscape, which may include the upregulation of LOC645023.
The complexity of cellular signaling is further exemplified by Lithium Chloride, which inhibits GSK-3 and can thereby influence the phosphorylation state and activity of proteins regulated by GSK-3, including LOC645023. Similarly, compounds that modulate kinase activity or the state of acetylation within the cell, such as EGCG and Sulforaphane, can lead to modifications in kinase-dependent signaling pathways and antioxidant responses, respectively, which can result in the activation of LOC645023. Autophagy inducers like Spermidine can also affect protein activity through the enhancement of cellular recycling mechanisms.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Non-specific inhibitor of phosphodiesterases, raises intracellular cAMP and cGMP levels, can lead to activation of PKA and subsequent activation of cAMP-dependent proteins such as LOC645023. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Direct activator of protein kinase C (PKC) which can modulate signaling pathways and proteins downstream of PKC, including LOC645023. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Calcium ionophore that can increase intracellular calcium concentrations, affecting calcium-dependent proteins and signaling pathways that can activate LOC645023. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Inhibits glycogen synthase kinase-3 (GSK-3) and can modify signaling pathways, leading to the activation of proteins regulated by GSK-3, including LOC645023. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Histone deacetylase inhibitor that can alter gene expression profiles and possibly lead to the upregulation and activation of proteins such as LOC645023. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A polyphenol that can affect multiple signaling pathways, including those related to kinase activity, thus can activate proteins like LOC645023. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Activates sirtuins and AMPK pathway, can impact proteins involved in these signaling pathways, including LOC645023. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Modulator of NF-kB signaling pathway, can induce the activation of proteins regulated by NF-kB, such as LOC645023. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $56.00 $595.00 $173.00 | ||
Autophagy inducer that can affect cellular recycling processes and can activate proteins that are regulated through autophagic pathways, including LOC645023. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
NAD+ precursor, can influence sirtuin activity and other NAD+-dependent processes, potentially activating proteins such as LOC645023. | ||||||