LOC644012 Inhibitors
LOC644012 inhibitors like Cycloheximide and Rapamycin are chosen for their capacity to inhibit protein synthesis and mTOR signaling, respectively. By suppressing these fundamental processes, these compounds can reduce the production and accumulation of proteins within cells, which includes LOC644012. WZB117 and 2-Deoxy-D-glucose are included due to their effects on cellular energy production. By limiting energy availability, these inhibitors can exert stress on cellular processes that depend on energy, which may include the activities of LOC644012.
Compounds such as Bafilomycin A1 and Thapsigargin are tasked with disrupting intracellular trafficking and calcium homeostasis. Altered intracellular environments and ionic balances can broadly impact protein function, potentially extending to LOC644012. On the other hand, kinase inhibitors like U0126, SB203580, LY294002, SP600125, PD98059, and Wortmannin are included because of their roles in modulating cell signaling pathways. These pathways are critical for a variety of cellular functions, including the regulation of protein expression and activity. Thus, by targeting these kinases, the inhibitors could modify the signaling environment and indirectly affect LOC644012.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits protein synthesis by interfering with the translocation step in protein synthesis, possibly reducing the overall levels of LOC644012 if it is actively synthesized. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR signaling which can downregulate protein synthesis and cell proliferation, potentially reducing LOC644012 levels or activity. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $48.00 $122.00 $432.00 $812.00 | 4 | |
Inhibits glucose transporter 1 (GLUT1) and can reduce the energy supply to cells, possibly affecting cellular processes that LOC644012 is involved in. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
A specific inhibitor of vacuolar type H+-ATPase (V-ATPase), which can affect endosome/lysosome acidification, potentially influencing the cellular trafficking of proteins like LOC644012. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
A glycolysis inhibitor that can reduce ATP production, possibly affecting cellular processes that require energy, including the function or synthesis of LOC644012. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibits p38 MAP kinase, potentially altering stress response and inflammatory processes that might affect LOC644012's function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, potentially affecting the PI3K/Akt signaling pathway and various cellular processes including those associated with LOC644012. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, which could affect cellular stress response pathways and potentially influence the activity of LOC644012. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK1 and MEK2, potentially affecting the MAPK/ERK signaling pathway and the activity or expression of LOC644012. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A potent PI3K inhibitor, which can affect various signaling pathways and cellular processes, potentially including those where LOC644012 is involved. | ||||||