The term LOC642426 Inhibitors designates a specific class of chemical compounds intricately designed to modulate the activity of LOC642426, a molecular target that is currently the subject of scientific investigation. These inhibitors are meticulously crafted through the principles of medicinal chemistry, with a primary focus on selectively interfering with the normal functions of LOC642426 within cellular processes. The structural features of LOC642426 Inhibitors are refined through iterative processes, often involving computational modeling and structure-activity relationship studies, to optimize their molecular configurations for precise binding to the target.
The significance of LOC642426 Inhibitors lies in their potential to disrupt the biochemical activities associated with LOC642426, a molecular entity believed to be involved in various biological pathways. Researchers in this field delve into the three-dimensional structure of LOC642426 and its binding interactions with inhibitors, aiming to unravel the intricate molecular mechanisms underlying inhibition. The study of LOC642426 Inhibitors contributes to a broader understanding of cellular processes, offering insights into the roles played by LOC642426 in diverse biological pathways and expanding our knowledge of the regulatory networks governing cellular activities. This research not only advances our comprehension of the molecular intricacies surrounding LOC642426 but also contributes to the broader scientific understanding of molecular targets and their involvement in fundamental cellular functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin can inhibit RNA polymerase II, which is responsible for transcribing mRNA and many non-coding RNAs, including lncRNAs like lincRNA 2297. This inhibition can lead to decreased RNA synthesis. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
RG108 is a DNA methyltransferase inhibitor that could prevent the methylation of DNA, a modification that typically suppresses gene expression. This might result in altered expression of genes, including those coding for lncRNAs such as lincRNA 2297. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine incorporates into RNA and DNA and inhibits DNA methyltransferases, potentially leading to hypomethylation of genomic DNA and affecting the expression of lncRNAs such as lincRNA 2297. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Decitabine is another DNA methyltransferase inhibitor that can lead to DNA demethylation and could potentially alter the expression of lncRNAs like lincRNA 2297 by changing the epigenetic state of their gene loci. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
JQ1 is a small molecule that inhibits BET bromodomain proteins, which can affect the expression of various genes, potentially including those encoding lncRNAs by altering the chromatin state and affecting transcriptional initiation and elongation processes. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
Entinostat is a histone deacetylase inhibitor that can lead to a more open chromatin state, potentially modulating the expression of lncRNAs such as lincRNA 2297 by affecting transcriptional regulation. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, inhibiting RNA polymerase and thus transcription. This can lead to a decrease in RNA synthesis, including that of lncRNAs like lincRNA 2297. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Cordycepin is an adenosine analog that terminates RNA chain elongation by inhibiting polyadenylation. This could potentially reduce the stability and thus the levels of lncRNAs like lincRNA 2297. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB is an adenosine analog that inhibits RNA polymerase II transcriptional elongation, which could lead to reduced expression of lncRNAs such as lincRNA 2297. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin has been shown to modulate gene expression and possesses RNA-binding capabilities, which could theoretically affect the stability and expression of lncRNAs like lincRNA 2297. | ||||||