LOC441617 Inhibitors
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Items 1 to 10 of 21 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Phorbol esters like Phorbol 12-myristate 13-acetate (PMA) activate protein kinase C (PKC), which in turn can lead to the activation of LOC441617 if it is a substrate of PKC or is regulated by downstream PKC pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor that leads to reduced AKT phosphorylation, which may indirectly inhibit LOC441617 if the protein's function is AKT-dependent. The absence of AKT activation can result in decreased cell survival signals, potentially reducing LOC441617's activity if it is involved in such survival pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor that blocks the PI3K/AKT pathway, potentially leading to reduced activity of LOC441617 by preventing AKT-mediated signaling processes that might be necessary for LOC441617's function. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, potentially activating calcium-dependent proteins and enzymes that could interact with and activate LOC441617. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
MEK inhibitor that impedes the MAPK/ERK pathway, potentially decreasing LOC441617 activity if it is regulated by or involved in this pathway's signaling events, such as cell proliferation or differentiation. | ||||||
1,2-Dioctanoyl-sn-glycerol | 60514-48-9 | sc-202397 sc-202397A | 10 mg 50 mg | $47.00 $254.00 | 2 | |
This synthetic diacylglycerol analogue can activate PKC. PKC can phosphorylate and activate proteins including potentially LOC441617 if it is part of the PKC signaling pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
A selective inhibitor of MEK, which could lead to the inhibition of LOC441617 by blocking the activation of ERK, a kinase that could be upstream of LOC441617's activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor that could indirectly inhibit LOC441617 by blocking mTORC1 activity, which could be upstream or synergistic with LOC441617's activity, particularly in protein synthesis and cell growth. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
Src family kinase inhibitor that might lead to decreased LOC441617 activity by inhibiting Src kinase signaling pathways, which may be necessary for the proper function or regulation of LOC441617. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
A tyrosine kinase inhibitor that could inhibit LOC441617 by blocking BCR-ABL and Src family kinases, potentially affecting the cellular context in which LOC441617 operates. | ||||||