Molecular structure of 1,2-Dioctanoyl-sn-glycerol, CAS Number: 60514-48-9
1,2-Dioctanoyl-sn-glycerol (CAS 60514-48-9)
See product citations (2)
Alternate Names:
1,2-Dioctanoyl-sn-glycerol is also known as 1,2-bis(O-octanoyl)-sn-glycerol.
Application:
1,2-Dioctanoyl-sn-glycerol is a cell-permeable analog of diacylglycerol and activator of protein kinase C (PKC).
CAS Number:
60514-48-9
Purity:
≥95%
Molecular Weight:
344.49
Molecular Formula:
C19H36O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1,2-Dioctanoyl-sn-glycerol is a cell-permeable activator of protein kinase C (PKC). 1,2-Dioctanoyl-sn-glycerol exhibits lower affinity for PKCa than for other isozymes. 1,2-Dioctanoyl-sn-glycerol is shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells. 1,2-Dioctanoyl-sn-glycerol is an analog of the lipid second messenger diacylglycerol (DAG).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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1,2-Dioctanoyl-sn-glycerol (CAS 60514-48-9) References
- Human immunodeficiency virus (HIV-1) cytotoxicity: perturbation of the cell membrane and depression of phospholipid synthesis. | Lynn, WS., et al. 1988. Virology. 163: 43-51. PMID: 3126600
- Enhancement of membrane permeability to a poorly absorbed drug by medium-chain glycerides: effect of medium-chain glycerides on the release of phenol red from egg phosphatidylcholine liposomes. | Higaki, K., et al. 1988. Chem Pharm Bull (Tokyo). 36: 1214-7. PMID: 3409403
Inhibitor of:
δ-casein, C8orf73, LOC441617, ZFP677, ZFP692, and Zfp735.Activator of:
β-1,4-Gal-T2, β-4-Gal-T4, γ-taxilin, 12-LO, 1600016N20Rik, 1700001N15Rik, 1700009P17Rik, 1700042B14Rik, 1700047I17Rik2, 1810030N24Rik, 2210404O07Rik, 2210411K11Rik, 2210415I11Rik, 2310033E01Rik, 2810008M24Rik, 2810011L19Rik, 3110007F17Rik, 3830431G21Rik, 3BP1, 4930408G06Rik, 4930455F23Rik, 6430628N08Rik, 9130409J20Rik, 9230107M04Rik, 9230110C19Rik, 9430007A20Rik, ACTR-IC, AJAP1, Annexin XI, ARHGAP20, ARHGAP4, ARHGAP9, AY026312, Aytl1b, B230218P12Rik, BANK1, BC016579, BC051142, Bcl-7a, C11orf21, C11orf24, C35, CaBP8, CAPS2, CARD 10, CASPR5, CCDC93, CD15, CD1B3, CD3-δ, CD8, CDP2, CDRT15L, CDS2, CIB3, CLEC-17A, COS5, cPKC α, cPKC βI, cryptdin 6, CXorf30, DANGER, DAP-4, DDTL, desmoglein 3, DGK-ι, DGK-κ, DGK-θ, DGS8, DNHD2, DOC2BL, dsg1γ, DUSP24, E430029J22Rik, Ena1, epiplakin 1, epsin 2, Esp3, Esp34, Etohi1, F8A1, F8A3, Fam148b, FAM148C, FAM153B, FAM160A2, FAM169A, FAM21B, FAM22F, FAM32A, FAM63B, FAM75A1, FAM75A3, FAM75A6, FAM75C1, FAM75C2, FAM75D4, FAPP2, FBF1, FLJ10489, FLJ37396, FLJ46321, FOXD4L1-6, FOXD4L5, FRMD8, GIMAP2, Glycophorin B, GPN3, GPR119, GPR75, granzyme B, IGSF22, IL-17C, ILT-5, Influenza A m1, IRGC1, Keratin 83, KIAA0528, KIAA1033, KRTAP10-4, LET-60 RAS, LOC100130172, LOC100130274, LOC100130705, LOC100130976, LOC100131831, LOC100132247, LOC100132396, LOC100132413, LOC100132963, LOC100133053, LOC100133267, LOC100133313, LOC100233207, LOC100287428, LOC100302652, LOC145814, LOC147670, LOC197350, LOC285141, LOC375190, LOC730094, LPAAT-β, LPCAT1, LRRC55, Ly-49L, Ly-49T, LYPD8, LYSMD3, MARVELD1, MIPOL1, Mog1p, MPP4, MPZL3, MRCKγ, MRP-L33, MRP-S2, MRP-S7, MS4A5, MS4A6E, MS4A7, MST-3, Mucin 7, Munc13-2, Myeov, NAT-16, NET-5, Nir1, NKHC1, Olfr867, Olfr870, Olfr902, Olfr904, Olr1517, Olr1520, Olr153, Olr1546, Olr1558, Olr1560, Olr1562, Olr1567, Olr157, Olr158, Olr1590, Olr1593, Olr160, Olr1607, Olr1622, Olr1630, Olr164, Olr180, Olr185, Olr193, Olr203, Olr210, Olr213, Olr222, Olr226, Opalin, Orai2, ORP-7_Osbpl7, ORP-8, OTTMUSG00000012557, OTTMUSG00000012817, PAFAH1B2, PAP21, PCTAIRE-2, Pellino 1, PI 4-kinase II β, PIRT, PKC, PKC γ, PKC ζII, PKC eta, PKD1, PLC ε2, PLC η1, PLC η2, Pleckstrin, PLEKHG3, PLP-B, PLP-Cβ, PLP-Cδ, PLP-F, PRAMEF21, PRB1, PRB3, PRR21, PRRG4, PSD4, PTTG2, Rag B, RasGRP3, RBMY1A, RGL3, Rhox7, Rhox9, RSPH9, Sec15B, SERINC1, SMAGP, SMEK1, SMPDL3A, SNAP 23, SNED1, SNX14, SPCA2, Speedy B, SPEER-3, SPEER-4B, SPEER-4D, SPEER-4F, StARD7, Synaptotagmin I/II, Synaptotagmin XII, Synaptotagmin XV, TCF23, TLE6, TMEM102, TMEM149, TMEM151A, TMEM155, TMEM16K, TMEM221, TMEM24, TMIGD2, TPD52, Tra-3, transportin 2, Trav12d-3, Trav12n-2, Trav13d-4, Trav14n-1, Trav16d, Trav4d-3, Trav4n-4, Trav6d-3, tricellulin, Trim12c, TRIQK, Trp4, TSPAN19, TSTD3, twisted, UNC93A, UNQ6126, V1RD17, V1RD19, V1RD20, V1RD22, V1RD4, V1rg10, VEPH1, VPS13A, XK, Xlr3a, ZFYVE27, ZNF132, ZNF324B, ZNF383, ZNF415, ZNF468, ZNF493, ZNF560, ZNF641, ZNF84, and ZSWIM2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,2-Dioctanoyl-sn-glycerol, 10 mg | sc-202397 | 10 mg | $46.00 | |||
1,2-Dioctanoyl-sn-glycerol, 50 mg | sc-202397A | 50 mg | $249.00 |