The term LOC439950 Activators refers to a class of chemical agents that specifically interact with and increase the activity of the protein product of the gene designated as LOC439950. This alphanumeric label indicates a locus or a specific position within the human genome that has been identified but whose gene product and associated functions may not be fully characterized. The 'LOC' prefix is commonly assigned to loci that are thought to represent putative protein-coding regions within the genome, and the succeeding number serves as a unique identifier for researchers to reference this specific genomic segment. Activators in this context are molecules that enhance the biological activity of the protein encoded by LOC439950. They may do so through various mechanisms, such as increasing the transcriptional rates of the gene, stabilizing the protein product to prolong its cellular lifespan, or facilitating its interactions with other proteins or biochemical pathways within the cell.
The discovery and development of LOC439950 activators would involve a multi-disciplinary approach, initially focusing on the characterization of the LOC439950 protein. If the protein's structure could be resolved through methods such as X-ray crystallography, NMR spectroscopy, or cryo-electron microscopy, this would provide invaluable insights into potential binding sites for small molecule activators. These activators would be designed to bind to the protein with high specificity, thereby enhancing its natural activity without disrupting other cellular mechanisms. Subsequent steps would include the synthesis of a diverse chemical library, with each compound designed to interact with the identified binding sites on the LOC439950 protein. Sophisticated high-throughput screening techniques would then be employed to test these compounds for their ability to modulate the protein's activity. Hits from this screening would be subjected to an iterative process of chemical modification to fine-tune their properties, such as binding affinity, specificity, and the ability to positively modulate the LOC439950 protein's activity. Through this cycle of design, testing, and refinement, effective LOC439950 activators would be developed, each uniquely crafted to engage with the protein product of the LOC439950 gene and elevate its functional state within the cellular context.
関連項目
Items 1 to 10 of 12 total
展示:
产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
可能影响 Wnt 信号通路,从而改变基因转录,并可能影响 ncRNA(包括反义 RNA)的水平。 | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
一种 DNA 甲基转移酶抑制因子,可导致 DNA 去甲基化,从而可能激活某些非编码 RNA 的转录。 | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
一种非核苷 DNA 甲基转移酶抑制剂,可导致 DNA 去甲基化,并有可能增强 ncRNA 的转录。 | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
一种组蛋白去乙酰化酶抑制因子,可改变染色质结构,有可能增加包括反义转录物在内的 ncRNA 的表达。 | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
一种植物提取的化合物,可调节多种信号通路,并可能通过其表观遗传效应影响 ncRNA 的表达。 | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
已被证明对基因表达有广泛影响,可能因其表观遗传调节能力而影响 ncRNA 的转录物。 | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
作为组蛋白去乙酰化酶抑制剂,它可以改变染色质动力学,并可能影响 ncRNA 的表达。 | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
十字花科蔬菜中的一种化合物,可影响基因表达,并可能通过表观遗传机制影响 ncRNA 水平。 | ||||||
(±)-Methyl Jasmonate | 39924-52-2 | sc-205386 sc-205386A sc-205386B sc-205386C sc-205386D sc-205386E sc-205386F | 1 g 5 g 10 g 50 g 100 g 500 g 1 kg | $35.00 $103.00 $200.00 $873.00 $1638.00 $6942.00 $12246.00 | ||
一种植物激素,可影响多种基因表达模式,可能包括反义 RNA 的转录。 | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
另一种 DNA 甲基转移酶抑制因子,可导致 DNA 的低甲基化,并可能影响 ncRNA 的转录。 |