The term LOC388282 Inhibitors refers to a class of chemical compounds specifically designed to modulate the activity of LOC388282, a molecular target whose detailed functions and biological roles may be subject to ongoing research. LOC388282 itself likely plays a crucial role in various cellular processes, and inhibitors within this class aim to interfere with its normal function. These inhibitors are meticulously crafted through medicinal chemistry approaches, involving the synthesis and optimization of chemical structures to achieve a high level of selectivity and potency in inhibiting LOC388282.
The chemical structures of LOC388282 Inhibitors are characterized by specific molecular features that facilitate binding to the target site on LOC388282, disrupting its normal biochemical activities. The development of these inhibitors often involves a combination of computational modeling, structure-activity relationship studies, and iterative synthesis to fine-tune their properties. Researchers focus on understanding the three-dimensional structure of LOC388282 and the binding interactions between the inhibitor and the target to enhance the efficacy of the inhibitors. The detailed investigation of LOC388282 Inhibitors is pivotal not only for understanding the biological functions of LOC388282 but also for potential applications in various research fields.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound is a DNA methyltransferase inhibitor. It could hypothetically inhibit LOC388282 by reducing methylation levels, leading to increased gene transcription. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Similar to 5-azacytidine, decitabine may inhibit DNA methyltransferases, potentially leading to demethylation and activation of gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor. It could hypothetically increase acetylation of histones, leading to a more open chromatin structure and potentially affecting LOC388282 expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
As another histone deacetylase inhibitor, vorinostat may change the chromatin structure and thereby potentially influence the expression of LOC388282. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $196.00 | 9 | |
Panobinostat inhibits histone deacetylases, which might lead to altered expression of many genes, possibly including LOC388282. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
This compound intercalates into DNA and inhibits RNA polymerase, which could lead to a decrease in gene expression, including potentially LOC388282. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Rifampicin binds to the bacterial RNA polymerase, and while it's specific to bacteria, if LOC388282 has bacterial origins, it could hypothetically inhibit its expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin is an inhibitor of RNA polymerase II in eukaryotes and could potentially reduce the expression of LOC388282 by inhibiting mRNA synthesis. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin A binds to DNA and inhibits RNA synthesis, which could potentially affect the expression of LOC388282. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine intercalates into DNA. Though it is mainly used for other applications, its DNA-binding property might hypothetically influence the expression of certain genes. | ||||||