Date published: 2025-11-1

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LOC100041450 Inhibitors

LOC100041450 inhibitors may include Wortmannin and U0126 inhibitors that target the PI3K/AKT and MAPK/ERK pathways, respectively, both of which are critical for numerous cellular functions including growth, survival, and differentiation. Their inhibition can result in the modulation of protein activities within these pathways, including potentially that of LOC100041450. MG132 and Bortezomib function by inhibiting the ubiquitin-proteasome system, leading to reduced protein degradation and possible accumulation of proteins within the cell, thereby exerting an effect on the functional state of LOC100041450. Ibrutinib and Z-VAD-FMK exert their effects through inhibition of tyrosine kinase-mediated signaling and blockade of apoptosis, respectively. If LOC100041450 is part of or influenced by these processes, its activity can be modulated by these inhibitors.

NF449 and PD173074 offer examples of inhibitors that act on G-protein coupled receptor pathways and growth factor signaling, both of which are essential for transmitting extracellular signals to intracellular endpoints. Furthermore, Trichostatin A can lead to changes in chromatin structure and gene expression, which may impact the synthesis or function of LOC100041450. KN-93, by inhibiting CaMKII, affects calcium-dependent signaling pathways, which are pivotal for a wide array of cellular responses. Dorsomorphin, by inhibiting BMP signaling, could influence developmental and morphogenic processes.

Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

A PI3K inhibitor, can prevent phosphorylation events within the PI3K/AKT pathway, possibly affecting LOC100041450 activity if it is PI3K/AKT pathway-dependent.

SB 202190

152121-30-7sc-202334
sc-202334A
sc-202334B
1 mg
5 mg
25 mg
$30.00
$125.00
$445.00
45
(1)

A p38 MAPK inhibitor, can alter stress response signaling pathways and potentially modulate the activity of LOC100041450 if it is involved in such pathways.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$56.00
$260.00
$980.00
163
(3)

A proteasome inhibitor, can lead to increased protein levels by preventing degradation, which can influence the functional state of LOC100041450.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$132.00
$1064.00
115
(2)

Another proteasome inhibitor, can similarly lead to accumulation of proteins and potentially alter the function of LOC100041450.

Ibrutinib

936563-96-1sc-483194
10 mg
$153.00
5
(0)

A Bruton's tyrosine kinase inhibitor, can change B-cell receptor signaling, potentially affecting LOC100041450 if it is part of this pathway.

Z-VAD-FMK

187389-52-2sc-3067
500 µg
$74.00
256
(6)

A pan-caspase inhibitor, can prevent apoptosis and may influence LOC100041450 activity if it plays a role in apoptotic processes.

NF449

627034-85-9sc-478179
sc-478179A
sc-478179B
10 mg
25 mg
100 mg
$199.00
$460.00
$1479.00
1
(0)

A selective Gs-alpha subunit inhibitor, can affect G-protein coupled receptor signaling pathways, potentially modulating LOC100041450.

PD173074

219580-11-7sc-202610
sc-202610A
sc-202610B
1 mg
5 mg
50 mg
$46.00
$140.00
$680.00
16
(1)

A FGFR inhibitor, can affect growth factor signaling, potentially influencing LOC100041450 if the protein is involved in such pathways.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

A histone deacetylase inhibitor, can alter gene expression profiles, which may affect LOC100041450 expression or function.

KN-93

139298-40-1sc-202199
1 mg
$178.00
25
(1)

An inhibitor of CaMKII, can modulate calcium signaling pathways and potentially affect LOC100041450 if it is calcium-dependent.