Date published: 2025-11-1

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LOC100040781 Inhibitors

The chemical class designated as LOC100040781 Inhibitors encompasses a series of specialized compounds designed to inhibit the activity of the gene product expressed by LOC100040781. This gene, identified through in-depth genomic analysis, has been recognized for its role in various cellular processes and functions. The expression and function of LOC100040781 are highly dependent on the specific cellular context and are influenced by various external environmental factors. Inhibitors targeting this gene have been meticulously developed to selectively bind to the proteins or enzymes that are the result of LOC100040781 expression. This selective binding is crucial, as it allows these inhibitors to directly impact the biochemical pathways involving the LOC100040781 gene product. By modulating the activity of this gene product, these inhibitors aim to alter the associated cellular processes, thereby influencing specific cellular functions and mechanisms.

The development of LOC100040781 Inhibitors is a complex and multifaceted task that involves integrating principles from molecular biology, chemistry, and bioinformatics. The process begins with a comprehensive understanding of the structural and functional aspects of the LOC100040781 gene product. Techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computational molecular modeling are employed to gain detailed insights into the target molecule. This foundational knowledge is essential for the rational design of inhibitors that are both effective in their interaction and highly selective for their target. Typically, these inhibitors are small molecules, crafted for efficient penetration into cellular membranes and for establishing a stable and effective interaction with their target. The molecular design of these inhibitors is carefully optimized to ensure robust interactions with the target molecule, often involving hydrogen bonds, hydrophobic interactions, and van der Waals forces. The efficacy of these inhibitors is rigorously tested through various biochemical assays in vitro. These assays are critical for determining the potency, specificity, and overall behavior of the inhibitors in controlled experimental conditions. Such studies provide essential insights into the inhibitors' mechanism of action and interaction dynamics, paving the way for further research into their potential impact on cellular pathways and functions.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

Vorinostat inhibits histone deacetylases, which could lead to changes in chromatin structure and potentially downregulate gene expression.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This DNA methyltransferase inhibitor could lead to DNA demethylation and potentially affect gene expression patterns.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

Similar to 5-Azacytidine, decitabine could induce DNA demethylation and alter gene expression.

MS-275

209783-80-2sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$24.00
$88.00
$208.00
24
(2)

As a histone deacetylase inhibitor, entinostat may modify chromatin and influence gene transcription.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$128.00
$505.00
2
(1)

RG108 may inhibit DNA methyltransferases, potentially affecting methylation status and gene expression.

Histone Lysine Methyltransferase Inhibitor Inhibitor

935693-62-2 free basesc-202651
5 mg
$148.00
4
(1)

This inhibitor of histone methyltransferase G9a may alter histone methylation and affect gene expression.

(±)-JQ1

1268524-69-1sc-472932
sc-472932A
5 mg
25 mg
$226.00
$846.00
1
(0)

JQ1 inhibits BET bromodomain proteins, potentially impacting the transcription of certain genes.

Mocetinostat

726169-73-9sc-364539
sc-364539B
sc-364539A
5 mg
10 mg
50 mg
$210.00
$242.00
$1434.00
2
(1)

Mocetinostat is a histone deacetylase inhibitor that might modify chromatin structure and influence gene expression.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

This compound is a histone deacetylase inhibitor that can alter chromatin structure and affect gene transcription.

Zebularine

3690-10-6sc-203315
sc-203315A
sc-203315B
10 mg
25 mg
100 mg
$126.00
$278.00
$984.00
3
(1)

Zebularine is a cytidine analog that can be incorporated into DNA and inhibit DNA methylation, affecting gene expression.