LOC100039786 inhibitors encompass a specific class of chemical compounds developed to target and inhibit the activity of the protein encoded by the gene LOC100039786. Identified through genomic research, this gene is known for its unique expression patterns, indicating a potential role in specialized cellular functions. While the full biological significance of the protein encoded by LOC100039786 has not been completely elucidated, preliminary genomic and proteomic studies suggest its involvement in certain cellular pathways. The development of inhibitors for this protein requires a comprehensive understanding of its molecular structure and the functional mechanisms it employs within cells. The primary aim of designing LOC100039786 inhibitors is to disrupt the protein's functional interactions within the cellular environment, thereby shedding light on its role in various processes and potentially influencing these mechanisms. This objective involves identifying essential domains or active sites on the protein that are crucial for its activity and crafting molecules that can effectively target and inhibit these sites.
The process of developing LOC100039786 inhibitors is a complex and interdisciplinary endeavor that combines expertise from the fields of biochemistry, molecular biology, and pharmacology. Researchers dedicated to this task focus on unraveling the structural details of the LOC100039786 protein. Employing advanced analytical techniques, they aim to determine the protein's three-dimensional structure, particularly highlighting areas that are significant for its functionality. This structural understanding is pivotal for the targeted design of inhibitors that are specific and effective in their inhibitory action. The interaction between these inhibitors and the LOC100039786 protein is a key factor in their efficacy. These inhibitors must bind to the protein in a way that interferes with its normal interactions within the cell, typically leading to the formation of a complex that inhibits the protein's typical functions. This interaction requires a precise alignment of the molecular structures of the inhibitor and the protein. Beyond their binding characteristics, the design of LOC100039786 inhibitors also takes into account factors such as the compound's stability, solubility, and its ability to effectively reach and interact with the target site within biological systems. Researchers also strive to optimize the pharmacokinetic properties of these inhibitors, ensuring they have appropriate hydrophobic and hydrophilic properties, and an optimal molecular size and shape for efficient interaction. The development of LOC100039786 inhibitors highlights the advanced level of current research in molecular targeting, underscoring the complexity involved in designing specific inhibitors for proteins that are relatively uncharacterized but may have significant roles in biological processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor that alters chromatin structure and can influence gene expression by changing histone acetylation states. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $206.00 $299.00 $485.00 | 10 | |
A PARP inhibitor that can affect DNA repair processes and potentially influence gene expression indirectly. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A natural compound that can modulate various signaling pathways and potentially downregulate gene expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
A polyphenol that can activate SIRT1, an NAD-dependent deacetylase, potentially influencing gene expression and longevity-associated pathways. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
An inhibitor of DNA topoisomerase I, leading to DNA damage and potentially affecting gene expression. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
A steroidal alkaloid that inhibits the Hedgehog signaling pathway, which can alter the expression of various genes involved in cell growth and differentiation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that can affect cell growth and proliferation pathways, potentially altering gene expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
A JNK inhibitor that may interfere with signal transduction pathways and alter gene expression profiles. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
An inhibitor of the TGF-beta receptor that can modulate TGF-beta signaling and affect gene expression. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A MEK inhibitor that may block the MAPK/ERK pathway, altering the regulation of gene expression related to cell proliferation and differentiation. | ||||||