LAT2 Activators
LAT2 Activators refer to a class of chemicals that can influence the activity or expression of the LAT2 (SLC7A8) protein, a transporter involved in the facilitated transport of neutral amino acids across cell membranes.
Among the chemicals associated with LAT2 activation, amino acids like leucine stand out. As an essential amino acid, leucine's presence in the extracellular environment can elevate the demand for amino acid uptake, subsequently influencing LAT2 activity. Similarly, insulin, a hormone central to various metabolic processes, can enhance amino acid uptake by upregulating transporters like LAT2 in certain tissues. Certain chemicals play roles in amino acid metabolism or cellular pathways that intersect with amino acid demand. For instance, glucose, a primary cellular energy source, may upregulate amino acid transporters like LAT2 under depleted conditions, as cells seek alternative energy pathways. Compounds like dexamethasone and epidermal growth factor (EGF) further exemplify the diverse mechanisms through which LAT2 activity can be modulated. Dexamethasone, a glucocorticoid, can influence protein synthesis, thus affecting amino acid uptake in certain cells. EGF can shape cellular growth and metabolism, subsequently impacting amino acid transporters.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
L-Leucine | 61-90-5 | sc-364173 sc-364173A | 25 g 100 g | $21.00 $61.00 | ||
An essential amino acid, its presence can increase the demand for amino acid uptake and might upregulate LAT2. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Can enhance amino acid uptake by upregulating transporters like LAT2 in some tissues. | ||||||
Taurine | 107-35-7 | sc-202354 sc-202354A | 25 g 500 g | $47.00 $100.00 | 1 | |
Known to modulate various transporters and may affect LAT2 indirectly. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A glucocorticoid that can influence protein synthesis and amino acid uptake in certain cells. | ||||||
D(+)Glucose, Anhydrous | 50-99-7 | sc-211203 sc-211203B sc-211203A | 250 g 5 kg 1 kg | $37.00 $194.00 $64.00 | 5 | |
A primary energy source that, when depleted, may upregulate amino acid transporters to compensate for energy demands. | ||||||
Palmitic Acid | 57-10-3 | sc-203175 sc-203175A | 25 g 100 g | $112.00 $280.00 | 2 | |
A fatty acid that can influence cellular metabolism and may affect LAT2 expression indirectly. | ||||||
Metformin-d6, Hydrochloride | 1185166-01-1 | sc-218701 sc-218701A sc-218701B | 1 mg 5 mg 10 mg | $286.00 $806.00 $1510.00 | 1 | |
An AMPK activator which can modulate cellular energy states and might influence LAT2 activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylate cyclase leading to increased cAMP, which can modulate various transporters. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, affecting protein synthesis and potentially amino acid transporter expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Known to affect various cellular pathways including those associated with metabolism and transport. | ||||||